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HARROW, INC. Call Transcript 2025

Nov 11, 2025

Call Transcript

HARROW, INC.

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Good day, and welcome to the Harrow Third Quarter 2025 Earnings Conference Call. At this time, all participants are in a listen-only mode. After the speaker's presentation, there'll be a question-and-answer session. Instructions will be given at that time. As a reminder, this call may be recorded. I would like to turn the call over to Mike Biega, Vice President of Investor Relations and Communications. Please go ahead. Thank you, Operator. Good morning, and welcome to Harrow's Third Quarter 2025 Earnings Conference Call. My name is Mike Biega, Vice President of Investor Relations and Communications, and I'm excited to be introducing today's call. Similar to our last quarterly call, we will be presenting slides during the webcast today. If you have registered and joined through the live conference call link, I would highly recommend that you also join through the webcast. You can find the link in the Investor section of our website at www.harrow.com or in our earnings press release that was issued yesterday. The company's remarks may include forward-looking statements within the meaning of federal securities laws. Forward-looking statements are subject to numerous risks and uncertainties, many of which are beyond Harrow's control, including risks and uncertainties described from time to time in its SEC filings, such as the risks and uncertainties related to the company's ability to make commercially available and FDA-approved products in compounded formulations and technology and FDA approval of certain drug candidates in a timely manner or at all. For a list and description of those risks and uncertainties, please see the Risk Factors section of the company's most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q filed with the Securities and Exchange Commission. Harrow's results may differ materially from those projected. Harrow disclaims any intention or obligation to update or revise any financial projections or forward-looking statements, whether because of new information, future events, or otherwise. This conference call contains time-sensitive information and is accurate only as of today. Additionally, Harrow will refer to non-GAAP financial metrics, specifically adjusted EBITDA and/or adjusted earnings, as well as core results such as core gross margin, core net income, and core diluted net income per share. A reconciliation of any non-GAAP measures with the most directly comparable GAAP measures is included in the company's earnings release and letter to stockholders, both of which are available on the website. Now, joining me on today's call are Mark L. Baum, Chief Executive Officer; Andrew Boll, President and Chief Financial Officer; and Patrick Sullivan, Head of Commercial. With that, I would like to turn the call over to Mark. Mark? Thanks, Mike, and good morning to everyone. Thanks for joining us today. As always, please review our supplemental documents for the third quarter, including our earnings release, corporate presentation, and letter to stockholders, all of which are now available on the Investor Relations section of our corporate website. During this call and in future quarterly conference calls, I'm pleased to have Pat Sullivan, Harrow's Head of Commercial, join us. Next quarter, I intend to have our Chief Scientific Officer, Amir Shojaei, join us as well. Today, Harrow is one of the leading providers of ophthalmic disease management solutions in North America. Our portfolio helps manage both front and back-of-the-eye conditions, and I believe we are the only ophthalmic company in the world to offer branded, generic, over-the-counter, compounded, and biosimilars, literally every legally available type of ophthalmic medication. At the center of everything we do is our vision to become the next great U.S. ophthalmic company. Now, 12 years into building this patient and physician-centric business, I believe we're still just getting started. Our key products are in their early stages of launch, with tremendous and durable growth ahead as adoption continues to accelerate. Over the next two years, we have four new product launches scheduled, each representing a significant opportunity to expand our reach, strengthen our leadership, and pave the way for even greater growth in the future. I am particularly proud of the fully scalable commercial infrastructure we've built, which will soon support multiple launches and continued expansion without requiring heavy additional investment. Combine that with a low-risk, capital-efficient pipeline development and M&A strategy, and it's clear Harrow's growth and market impact are in their infancy. Now, our momentum continued during the third quarter with rising revenue and clear evidence of the operating leverage in our business model. As I've mentioned before, some areas of our business will overperform, while others may lag, sometimes due to seasonal factors, and the third quarter was no exception. What matters most, though, is the overall trajectory of the business, and that trajectory remains very strong. Our key growth engines, such as VEVYE, IHEEZO, and, to a certain extent, beginning very recently, TRIESENCE, are rolling, and momentum continues to build across the business, especially as we approach the launch of the Samsung Bioepis biosimilar portfolio and conclude the acquisition of Melt Pharmaceuticals, which I'm very excited about. Now, VEVYE and IHEEZO continue to lead the way and are on track to finish the year very strong. In fact, 2025 is expected to be a record year for both products. They've shown consistent momentum and continue to drive the majority of our growth. Driven by strong demand and best-in-class clinical performance, VEVYE delivered 22% quarter-over-quarter revenue growth. Perhaps a key highlight of my remarks, though, should be the news that we have recently signed agreements with several leading national payers for VEVYE. Beginning in January 2026, only a couple of months away, VEVYE will be listed on multiple new formularies with a preferred product status, including the largest U.S. Pharmacy Benefit Manager. This means that certain products are becoming uncovered, and that creates an opportunity for prescription transfers. Going forward, VEVYE will be covered on those formularies. This particular PBM covers tens of millions of lives, and I view this as a major development for VEVYE and for Harrow. With major improvements in coverage and the addition of ApolloCare and Alto joining our specialty pharmacy network this quarter, we expect a higher proportion of patients will receive VEVYE as a covered therapy. These advancements strengthen VEVYE's market access foundation and fuel continued prescription growth, resulting in an improved ratio of covered to cash pay prescriptions. This includes estimates of current cash pay patients who are likely to convert to covered prescriptions, and that gives us confidence in VEVYE's pricing stability and long-term growth. IHEEZO also had an excellent quarter, delivering 20% quarter-over-quarter revenue growth. That's an impressive performance given the typical seasonal slowdown for that product in the third quarter. Meanwhile, TRIESENCE and our rare and specialty portfolio underperformed this year, as I talk more about in our stockholder letter, and that also included the third quarter. The good news, though, is that we have the right leadership and strategies in place, I believe, to get both on track in short order. TRIESENCE, in particular, is gaining traction in retina, and as of October of this year, we launched it in its largest market opportunity yet, ocular inflammation. Our rare and specialty portfolio also has new leadership, and they are supporting our Harrow Access for All program, which is positioned to return this portfolio to growth beginning in the fourth quarter and into 2026. Please review the letter to stockholders for more specific thoughts, though, on TRIESENCE and our rare and specialty products portfolio. We also made important strategic moves this quarter as we worked to complete the acquisition of Melt Pharmaceuticals and its non-opioid procedural sedation candidate, Melt 300, and we also expanded our Access for All model across our entire ophthalmic portfolio. We're also preparing for four product launches over the next three years: BioViz, OpioViz, Biclovi, and Melt 300, which I'm particularly excited about. In short, our strategy is bearing fruit. We're executing with discipline, scaling with purpose, and building a company defined by innovation, access, and sustainable growth, creating meaningful long-term value for both patients and shareholders. Before I hand it over to Andrew, I want to take a moment to address our ImprimisRx business in California, where, as many of you know, we have been engaged in a dispute with the California Board of Pharmacy for many years. ImprimisRx remains licensed to operate in California, but its license is up for renewal on December 1, 2025. We are actively communicating with the California Board towards a global resolution, which would include a renewal of our license. Because these discussions are ongoing and, frankly, no outcome can be certain, I can't comment on other specific details, but this is top of mind for us, and we believe a solution may be at hand. As more information becomes available, we will communicate with our stockholders. With that, I would like to now turn it over to our President and Chief Financial Officer, Andrew Boll. Andrew? Thanks, Mark, and thank you to everyone joining the call today. Turning now to our financial performance, total revenue for the third quarter was $71.6 million, representing a 45% increase over the same period in 2024 and a 12% sequential increase from the second quarter of this year. For the first nine months of 2025, total revenue reached $183.2 million. We remain firmly on track for another strong year of revenue growth, advancing toward our long-term financial targets with disciplined execution. Based on what we're seeing across the business today, which I'll walk through in greater detail in the next slide, we are updating our full-year revenue outlook to a range of $270-$280 million. While hitting our original target of over $280 million is still within reach, we want to take a slightly more conservative approach and update guidance for a range we believe we can deliver on. Adjusted EBITDA for the third quarter was $22.7 million, with GAAP-based net income of $1 million. Operating expenses continue to be relatively stable quarter to quarter, and we are seeing more operating leverage manifest itself within the new revenue gains. As we continue to scale, our ability to translate revenue growth into earnings remains a core strength of Harrow's model. As we advance into the fourth quarter, we expect to see operating expenses moderately increase as further investments are made in our commercial infrastructure to accelerate sales, and that trend should continue into 2026. Let's turn to our product performance. VEVYE continues to outperform, generating approximately $22.6 million in revenue during the third quarter. This is a 22% increase from the second quarter of 2025. This revenue increase was driven on continued increase in unit volumes year-over-year and quarter-over-quarter. VEVYE is set up for a record fourth quarter. October hit an all-time high in prescriptions, and that momentum has carried right through the first week of November. Q4 was VEVYE's strongest period last year, and with the trends we're seeing, I'm confident we're on track to finish near our $100 million annual revenue target for 2025, with additional meaningful growth expected in 2026 as improved coverage kicks in and we further invest into VEVYE's commercial infrastructure to fuel the next phase of growth. Turning to IHEEZO, revenue for the third quarter came in at $21.9 million. This is up 20% from the second quarter. As we've seen in prior years, the third quarter tends to be seasonally softer due to the July and August slowdown as both patients and physicians take time off. That said, demand rebounded sharply in September and remained strong through October. IHEEZO has significantly outperformed our expectations this year and is also on track for a very strong fourth quarter and a record year. The fourth quarter has historically been IHEEZO's highest volume quarter, supported by end-of-year ordering patterns and stocking activity, and we've already seen large orders placed early in the period. Based on those dynamics, we expect IHEEZO to deliver a strong close to 2025. Our TRIESENCE and broader specialty branded portfolio generated $6.9 million in revenue. This is a 33% sequential increase. As Mark discussed and highlighted in our letter to stockholders, with new leadership in place, a dedicated sales force, the launch of Harrow Access for All, and TRIESENCE's launch into ocular inflammation, we now have the focus and strategies in place to reignite growth, starting as early as the fourth quarter of this year. ImprimisRx products continue to provide stable recurring revenue, generating approximately $20.1 million in revenue in the third quarter. As Mark mentioned earlier, if we are unable to resolve the dispute with the California Board of Pharmacy, we may see a minor impact on ImprimisRx's fourth quarter revenue. In addition, ImprimisRx had an inventory shortage during the month of October, causing a one-time decrease of about $4–$6 million in its revenue for the fourth quarter. In summary, we are fully focused on achieving our third consecutive year of 40% or higher annual revenue growth, with all hands on deck across the organization. VEVYE and IHEEZO are both positioned for a strong finish to the year and a record quarter. However, given the certain near-term factors, we're updating our full-year outlook to a range of $270–$280 million. While our original target is still within reach, this new range is a one I believe we can deliver on based on where we are today. That said, the fundamentals of our business remain strong, and I could be more confident in the long-term growth trajectory. Looking ahead, following what we expect to be a strong fourth quarter, we anticipate a typical seasonal decline from Q4 2025–Q1 2026, likely consistent with the pattern we saw earlier this year. This does not mean that we will not achieve record results next year, which is what we expect to happen. However, we want to establish that Q1 presents a seasonality that we need to consider. I will provide more color on the magnitude of that dynamic when we report full-year results, including the expected impact from the fourth quarter stocking activities. Thanks, Andrew. My responsibility as Harrow's commercial leader is crystal clear: unlock the massive commercial potential in our portfolio and position Harrow for sustained, profitable growth. As many of you know, I've been in this role for less than six months, but I am not new to commercial leadership, building successful teams to execute thoughtful strategies and ultimately delivering extraordinary results. I would like to highlight the five commercial priorities that will drive my team's efforts. First, we're activating our advanced key account management initiative. This is about deepening relationships with high-value accounts, fueling trial, accelerating adoption, and building long-term loyalty across the brands. Second, we're elevating our focus on driving depth and breadth, expanding our reach to more prescribers and new accounts while going deeper within existing users. This is key to unlocking the full potential of our portfolio. Third, we have a scalable investment model across the commercial organization, one that allows us to grow efficiently, invest intelligently, and maximize return on every dollar spent. Fourth, we're expanding awareness of our Harrow Access Solutions program to ensure a smooth and positive experience for both eye care professionals and their patients. Removing barriers to access remains a cornerstone of our strategy. Finally, we're sustaining operational discipline and stability, maintaining an efficient cost base while continuing to execute at a high level. These commercial acceleration priorities position us to drive stronger adoption, profitable growth, and continue our journey as an emerging leader in the ophthalmic market. VEVYE continued to strengthen and expand its position in the dry eye market during the third quarter, delivering strong and sustained growth. Our commercial strategy is working. We're seeing increasing physician confidence, excellent patient outcomes, and faster, more affordable access to therapy. By the end of September, we saw a 36% increase in prescribing physicians, a strong indicator of continued growth and expanding physician adoption. Our VEVYE Access for All initiative remains a key enabler of growth for VEVYE, simplifying the patient experience and fueling demand. Starting in January, VEVYE will appear on several new national formularies with preferred status, including the largest Pharmacy Benefit Manager in the United States. VEVYE's improving coverage serves as another catalyst to expand utilization among eye care physicians and among more patients with dry eye disease. We anticipate that these increased coverage wins. Many current cash-pay patients will take advantage of VEVYE's improved coverage in their plans. We also expanded our specialty pharmacy network. PhilRx handled all prescriptions in Q3, while ApolloCare went live in Q4, and AltoRx will follow later this quarter. Steps to further improve patient access for patients. Combined with the broader payer coverage coming in 2026, these developments favorably position VEVYE for continued growth and pricing stability. Let's look at VEVYE's outlook. Looking at the chart on the top left, the picture is clear. The dry eye disease market is large, active, and growing. The branded segment is the key driver for growth in the overall market. By the end of the third quarter, VEVYE captured 10.5% of the total dry eye market, up 2.7 share points from the prior quarter, effectively doubling its market share in just two quarters. It's a clear sign of strong, sustained growth and proof that our strategy is delivering results. Our goal remains the same: to make VEVYE the number one prescribed cyclosporine therapy in the U.S., and we're making steady progress toward that. We're building momentum every quarter, increasing adoption, improving access, and expanding coverage, and we remain confident in our path to becoming the leading cyclosporine therapy in the dry eye space. Looking ahead, we're focused on accelerating growth through both depth and breadth, deepening utilization with existing eye care physicians while expanding use among new physicians and their patients. Now that we are comfortable with our supply, we are also preparing for the next phase of expansion with plans to invest in VEVYE's commercial infrastructure and open 10 additional sales territories to fuel the next phase of growth. We anticipate that more territories will open during the first half of 2026, and we are going to focus on markets served by the new plans that will cover VEVYE. The momentum behind VEVYE is clear. With growing adoption, strong clinical outcomes, a patient-centric access model, and improving coverage, we're just getting started. VEVYE has doubled its market share over the past two quarters, and with new investments in our commercial infrastructure to support the next phase of expansion, the opportunity ahead is tremendous. I'm confident our team is fully aligned and focused on making VEVYE the new standard of care for dry eye disease. Let's look at IHEEZO. IHEEZO had another excellent quarter. Unit demand was up 47% from last year and 3% sequentially. That's strong, sustained growth, and continued proof that IHEEZO's value proposition is resonating in the market. As expected, the third quarter followed normal seasonality. A brief slowdown in July and August, but demand rebounded quickly in September and continued through October. With a large order already placed in October, entering its strongest quarter of the year when we typically see increased stocking activity, IHEEZO is well positioned for a strong finish to 2025 and real momentum heading into 2026. Our strategy is working exactly as planned. The retina pivot we executed last year, along with our new IHEEZO for All education initiative, is driving awareness, engagement, and adoption across retina practices. Nearly half of the accounts ordering IHEEZO this year are brand new, a clear sign that we're expanding reach and deepening loyalty. With an 86% reorder rate, IHEEZO is not only winning new users but also keeping them, a strong foundation for sustained growth ahead. Looking ahead, we're still just scratching the surface of IHEEZO's potential. We're in the very early stages of this growth story, and the opportunity ahead is tremendous. Our retina team is focused on both driving both breadth and depth, reaching new accounts and deepening relationships with existing customers, and expanding awareness among retina specialists. As adoption continues to grow, we're confident that IHEEZO will become an even stronger growth engine for Harrow, especially once we introduce our biosimilars starting in mid-2026. Shifting to TRIESENCE. TRIESENCE is showing real progress in the retina market. The trends we're seeing now indicate an acceleration in adoption and growing traction across the retinal community. Since relaunching TRIESENCE last October in 2024, there has been a four-times growth factor with significant headroom remaining. TRIESENCE unit demand grew 67% sequentially. Importantly, more than half of the accounts ordering TRIESENCE in the third quarter, about 53%, were new customers. That tells us our reach is expanding and physicians are responding to TRIESENCE's strong clinical performance and favorable reimbursement profile. With its proven safety, excellent efficacy, and broad payer coverage, TRIESENCE is well positioned to continue gaining share in the retina market. The big news is our official launch of TRIESENCE into the ocular inflammation market, the largest and most promising opportunity for the brand to date. We're still early in the launch, but the response from the field has been encouraging. Physicians are giving strong positive feedback, and early utilization trends are moving in the right direction. The early traction reinforced exactly what we believed from the start: that TRIESENCE delivers real clinical value and fits seamlessly into physician workflows. We see this launch as a true catalyst, opening a major new growth channel for TRIESENCE. With proven safety, strong efficacy, and broad payer coverage, TRIESENCE is gaining traction in the retina market and has just entered its largest opportunity yet: ocular inflammation with positive early feedback. As awareness builds and adoption expands, I'm confident TRIESENCE will become a key growth driver and increasingly important contributor to Harrow's leadership in ophthalmic care. Turning to rare and specialty products, this is an area of untapped potential for Harrow. Earlier this quarter, we're excited to welcome Tom Pertallo as the Vice President of this segment. Tom brings deep commercial experience and a proven track record of driving growth, and his leadership comes at exactly the right time as we work to unlock the full value of this portfolio. Right now, these products represent less than 1% of the total market volume, which means the upside is significant. With Tom leading the charge and a dedicated sales force being built to focus exclusively on this business, we're tightening execution, re-energizing our commercial approach, and positioning these brands to return to growth. We're also launching the Harrow Access for All program this quarter, which will improve affordability and expand patient access. Key levers to drive sustainable growth across the portfolio. This portfolio once generated nearly $10 million quarterly revenue, and we see a clear path to reignite that growth and ultimately exceed those levels. With strong leadership now in place, renewed focus, and clear strategies in place, I'm confident this business is positioned to return for growth and deliver stronger, more consistent performance moving forward. To close, I couldn't be more excited about where Harrow is headed. We're still very early in the growth stages across all of our key growth drivers, with significant catalysts and ample room for further growth. We are well positioned for our next stage of growth. Our commercial momentum is strong, the plan is clear, and the opportunities in front of us are huge. In dry eye, VEVYE continues to lead the charge, expanding its share, broadening access, improving coverage, and deepening adoption among prescribers. In retina, we're strengthening relationships, expanding awareness, and gearing up for two major launches: BioViz in mid-2026 and OpioViz in mid-2027. In the surgical segment, we're building a differentiated portfolio that supports the perioperative space, delivering efficiency and value for practices. In rare and specialty, new leadership, a focused plan of action, and the launch of Harrow Access for All are unlocking the potential of a diverse portfolio that represents less than 1% of its addressable market today. The opportunity across these four segments is tremendous. With best-in-class products, a scalable commercial platform, and a disciplined strategy for execution, we're building a company with durable, long-term growth potential. Harrow's path forward is clear: stronger execution, expanding leadership, and sustained momentum across every part of the business. With that, we can turn it over to the operator for Q&A. If your question has been answered and you'd like to remove yourself from the queue, press star one again. Our first question comes from Jeffrey Cohen with Ladenburg. Your line is open. Hey, good morning. Thanks for taking our questions and congrats on the quarter. A couple from Aaron. Firstly, could you talk about VEVYE prescription data and why we do not see it this quarter? Hey, Jeff, this is Mark. Thanks for the question. What we decided to do is to make sure that we have the most accurate information available. As you know, we withdrew from some of the reporting services, some of the data reporting services, a few quarters ago. It is really important that we have confidence, absolute confidence, that what we are putting out is as accurate as possible. From our perspective, I think the key metric was revenue generated from these products and not necessarily IQ via data or data from a data feed that may or may not be completely accurate. Because of that, we decided to change the way that we're reporting. Andrew, do you want to add to that at all? Yeah, and thanks, Jeff. The only other part of that to add to what Mark was saying is really one of the reasons we kind of were pulling out of these third-party aggregators were for competitive reasons. If we're doing that, it didn't really make sense to us to present the data, to then present the data and make it available to all of our competitors in our earnings release. That's driven a lot of the decision-making with presentation of the TRX data. To Mark's point, we're going to do our best to be transparent about the progress of VEVYE without giving up competitive positioning. Okay, that's perfect. Secondly, maybe for you, Andrew, could you talk about the leverage that you're achieving? You had some pretty nice leverage on the SG&A in the third quarter, but as you continue to expand your commercial teams, how should we think about leverage overall into 2026, mainly as a percent of revenues? Yeah, and this has been a topic for us that we've brought up for a long time now, where we expected to see operating leverage, especially this year in the model on the new revenue growth we expected. We spent a lot of money on the operational and commercial infrastructure to support the branded group. That is mostly in place, and we're seeing that leverage show up in the numbers. Obviously, Q3, we had great Chad Brines just under $23 million. The business is producing a lot of cash, about $16 million of cash in the third quarter from operations. As we look out, Pat talked a little bit about adding to that commercial infrastructure to drive revenue. The additional OpEx that we're looking at is revenue-generating OpEx. We should start seeing immediate return on that expense. Again, even though we're going to be making investments in the commercial infrastructure, it's not like it's going to be a 50% increase in OpEx. It's going to be a moderate increase. Importantly, and this is probably the most important thing, that investment in the expense should see almost an immediate impact and return on revenue. Okay, got it. Thanks for taking our questions. Congrats on the quarter. Thank you, Jeff. Thanks, Jeff. Thank you. Our next question comes from Chase Knickerbocker with Craig Hallum. Your line is open. Good morning. Thanks for taking the questions. Maybe just first to start, a couple on VEVYE. Mark, you had mentioned in the stockholder letter that ASP was down modestly sequentially in Q3. Could you just define the magnitude of that modest decline for us just so we can kind of understand that? And then just as we think about, you kind of spoke to stabilization in the near term. Can you just walk us through some of your modeling assumptions on VEVYE that kind of lead to that ASP stabilization in the near term? Is it improving mix that you're seeing so far in October? And then I've got a follow-up. Thanks. Thanks for the question, Chase. In terms of defining what modestly means, I can't give you a definition with precision. I mean, I think it's less than 10%. I think the more important issue is how is ASP or net revenue per unit, how is that going to stabilize in the near term? Then, as I said on prior calls, begin to float up. What is the justification for that? To be very clear, we're really counting on coverage coming through. We're counting on the ratio of covered prescriptions versus cash-pay prescriptions to flip or begin to change so that there's more of a bias towards covered prescriptions versus cash-pay prescriptions. If that happens, that's when you see the stabilization happen. That's when you see the ASP begin to float up. The beautiful thing, I think, the exciting thing for us, and I think you've actually noted this in your notes that I've seen, is that that increase will affect the entire corpus, every single unit of VEVYE. The question is how and when is that going to happen? I tried to address that in the letter to stockholders. We discussed that in our prepared remarks. We now have landed this coverage win with the largest Pharmacy Benefit Manager in the U.S., and specifically their commercial lives group. You're talking about tens of millions of new potential lives covered. When you think about that ratio of covered prescriptions versus cash-pay prescriptions, beginning January 1, we anticipate that ratio is going to begin to flip. Actually, to be candid with you, I've had doctors send me letters that I know that have already gone out from this benefit manager to the physicians, letting them know about the plan changes that will take effect, drugs that will not be covered, and the specific patients' names who will no longer be covered for that product, and letting them know what the new formulary looks like. This is really exciting for VEVYE. We expect to start seeing some of those changes, those prescription flips from other dry eye products to VEVYE in the fourth quarter. We expect that'll start to happen, but it'll really kick in in the first quarter. As I said, once that takes place, that ratio of covered versus cash-pay will begin to change. You'll see that stabilization happen. I think, as I said in the last call, we'll start to see, I think, a bias towards ASP improving and potentially improving maybe even more than modestly. Yeah, that's what I was hoping to follow up on, is just any more specifics you'd be willing to share as far as that, the largest PBM, that win? Was it their commercial plans? Was it commercial and Medicare? Just any sort of details there. As we think about that ASP improvement, to your point, any way you can help us kind of define how you see your current volume and kind of the amount of your current volume that could benefit from that win and how that affects ASP and any thoughts you'd be willing to give there as we enter next year? Yeah, I would say that these are commercial lives, number one. They're, I would say, the most attractive of those lives that you can get. It's a major coverage win. I was talking to our team earlier, and I said, "I hope that our investors, the main takeaway from the stockholder letter, I think it's the most important part of the stockholder letter, is this coverage win because it dramatically changes things." I mean, if you get a $20 or $30 or $40 improvement, and I'm not suggesting that we'll see a $40 improvement on ASP, but if it's a $20 improvement, as an example, it affects every single one of those units. As units are growing, and they will grow regardless, we are going to see significant improvement in total units for VEVYE. The question is, how much money are we going to make from all of those units? I think that this improvement in coverage is going to be a major factor at the beginning of this coming year. You also know that we are very conservative in terms of how we invest commercially. We do not do extravaganza launches because we dip our toes into the water. We kind of get in. We see what works. It is just our style, and it is the way that we have been able to invest in new product launches. For us to now make investments in VEVYE and specifically open up 10 new territories in the very near term, I think by the middle part of next year, we are going to have upwards of about 100 total territories for VEVYE. The reason why we're making those investments is because, candidly, it would be malpractice for us not to make those investments now that we have such strong coverage in these specific markets. We're very bullish on VEVYE next year. I think you can expect to see some improvements in ASP as this ratio begins to flip and bias more covered versus cash-pay prescriptions. It's a really good time for VEVYE. The drug, by the way, is phenomenal. If you've ever put the drug in your eye, it's phenomenal. I think it's the best product in the class. It does a great job, and patients love it. The refill rates are absolutely extraordinary. I believe best in class. Very helpful caller, Mark. Thank you. Thanks, Chase. Thank you. Our next question comes from Steve Seedhouse with Cantor. Your line is open. Hey, good morning. Thanks for the question. Hoping just to start, you could give us a sense of what proportion of the VEVYE cash-pay patients currently you'd actually expect to transition to insurance coverage in 2026 and just ballpark the expected impact that that particular variable would have on net price per unit. Yeah, thanks for the question, Steve. I don't know that we can give you the answer with precision. We actually have built internal models to try and estimate what that would look like. This is the largest commercial PBM. If you just model out how many dry eye patients they have, and we do know how many dry eye prescriptions come from those plans, we can see a couple of things happening. One, as I said, there are patients that have been denied coverage from those plans who are paying cash, who we will be able to reach out to and hopefully transition them from cash-pay to cover because this is not just a non-preferred brand status. This is a preferred status, or this is the lowest, or in some cases, no copay type coverage. It is really favorable coverage for VEVYE. Of course, we, as I said, are seeing the letters that have already gone out to physicians, letting them know that legacy products that patients were being prescribed are no longer covered. I know what those specific products are. I was looking at the number of patients, of course, not looking at the specific patients' names or any of that, but just one physician in one small community on one street, the number of patients. You start adding up these letters going out to thousands and thousands of physicians, and it could absolutely hit what we are thinking about internally in our modeling. Andrew, do you want to add to that at all? Yeah, I think the one thing that I'm really excited about this coverage win is it kind of shows what the—and I think we're going to really see it next year as we demonstrate the power of VAPA, which is really a long—the VAPA program is almost called a temporary program. It's not meant to be the program forever. The goal of the program is to gain coverage wins and increase patient access through insurance reimbursement. Through that, we think ASP will improve. What's great about the program, though, is it also sets us up where we kind of have a base to work off of when we're negotiating with PBMs and payers. There's no reason for us to take less money from a payer. When we're bidding, we're not going to bid ourselves into a hole. The VAPA program is working really well. I mean, it's exceeding our expectations on the cash-pay side. What that's doing is setting us up for a lot of long-term growth for the product, especially as the insurance wins come in. We think they will. We think that the program itself, just with the volume and demand we're seeing, brings us more negotiating power when we go to the payers and go through these bid cycles. I think, like I said, the first coverage win is a good demonstration of that. We should see more of that in 2026 and 2027. I just want to ask, focusing on, I guess, fourth quarter specifically. On that point, you were just noting you're in this moment, right, where the volume growth is tremendous, and you have this sort of couple-month window between now and 2026 where it would be critical to keep people on drug until their insurance coverage kicks in. Are you doing anything like providing free prescriptions beyond the first month to VAPA patients or just anything new to bridge that gap given the new coverage decisions that would impact fourth-quarter revenue? On the flip side, just with the addition of the new specialty pharmacies, is there any expected inventory or stocking or sort of one-time impact to fourth quarter that we should be considering for our models? Andrew, why don't you take the last question, and I'll touch on the first question and ask Pat for some guidance as well. Yeah, on any inventory stocking, Steve, I don't think we'll see anything really that impactful with VEVYE in particular for the fourth quarter. These guys are ordering pretty almost just-in-time type ordering, not quite that regularly, but I would say they're taking less inventory than wholesalers typically would. No real end-of-year impact related to that. Specifically on keeping patients on therapy, I don't know that we want to go into any specific tactics, but I know that the dry eye team, Maria and her entire team are hustling. Pat, you want to add to that at all? Yeah, thanks, Mark. I think this is a super exciting opportunity, and this is part of the plan. I think, to me, we have a very, very clear activation plan to really take advantage of evolving from FAPA to support these patients to really capitalize on our managed care wins. I think, to me, it is very much focused on the communications that are happening from the plans at this point in time to their patients, making sure that doctors know about our VAPA program and these wins that are going to be taking place to ultimately support the patient at the end of the year. We have a very robust high-touch program that is taking place and activating as we speak now that will continue to wrap up the year to support these patients and really accelerate growth at the end of the year. I think, in addition, our program right now, our fill program in VAPA, is a very high-touch program. We have a very, very clear view into who the patients are that are coming on our product and that are eligible for conversion to this commercial win. Super exciting time. To answer your question, we have a very clear plan to really drive conversion and help these patients. I'll just add that I was excited. As soon as we got the coverage win, we got that information, I'll tell you, and it gave me a lot of confidence in Pat and Maria and the team. I mean, I think they even had a name for the plan internally that they were going to begin to execute. It was just a text message. It was just like, "Okay, let's fire it up." It just gave me a lot of confidence that we have the right people, we have the right strategy to take advantage of this great opportunity and continue the growth in VEVYE. Kudos to the work that Pat and Maria are doing. Thank you. Our next question comes from Mayank Mamtani with B. Riley Securities. Your line is open. Yes, good morning, team. Thanks for taking our questions and appreciate the detail on business momentum. Maybe just a higher-level question on sort of these 3Q to 4Q dynamics. Some you observed last year versus others you're talking to are unique to you this year. I was just curious if you could comment a little bit on the notably high sort of $80 million revenue threshold in 4Q. It's sort of sequentially double versus what you had in 3Q. And it seems a lot to be still driven by VEVYE, I think 60% over. Sequentially. Any color, Mark, you can give on volume versus price kind of dynamic here that you're assuming across the different product lines. And then I have a follow-up. On Q4, what I would say is I think last year, Andrew, Q4 was probably upwards of a third, maybe a smidge higher than a third of our overall revenue for the annual period. I wouldn't expect that to change this year. I think that we can do around that range this year. I think the exciting thing about Q4 for what it's worth is the emergence of TRIESENCE finally. I think I was quite candid in the letter. We could have done a lot better. We should have done a lot better with TRIESENCE. In every period this year, the first three periods, the same is true with our rare and specialty portfolio. The key is that we've taken action. TRIESENCE, I think we're seeing really exciting things, not just in words, but in deeds. As I was telling the team, we're not at a point where Mark can get on a conference call and say, "Hey, I'm really excited about TRIESENCE. I think this is going to be fantastic." It is time for orders. It is time for revenue. It is time for reorders. It is time for new accounts starting and adopting. Because I'm seeing that, I'm actually—I have been involved in the sales process myself. I have been communicating with high-volume surgeons and talking to them about TRIESENCE specifically. I'm actually seeing surgeries start with it. That is exciting. I have been through that cycle. I have seen that cycle. That gives me a lot of confidence in where we're going with that product, not only beginning to feather in in the fourth quarter, but really for next year. It's going to get to where we thought it would be. That's super important. In terms of other dynamics between Q3 and Q4, Andrew, do you want to comment on any of that? Yeah, Mike, I think we've kind of talked about VEVYE on the ASP side and expecting at least stabilization there. Typically, at the end of the year, your patients are out of that copay deductible and amounts like that. Our copay buy-downs are a little bit lower on a per-unit basis. Hopefully, that helps to see a little bit of price improvement. In general, the expectation is we're going to see volume improve across the portfolio. That'll drive most of the revenue growth for the quarter. Great. Actually, a couple of specific product-level questions. Project BYQLOVI enabled patients who crossed over to branded VEVYE. You may have some information there on the conversion rate from cash-pay maybe to commercial insurance coverage groups. I don't know if that was something you can share or has given you some learnings moving forward. On TRIESENCE, are you able to comment on what the new price point is? Looks like you're really focused on access to enable significant volume growth as you enter the ocular inflammation market. Obviously, very curious to hear your goal here, how close you are trying to get to when the product was not on the shortage list a few years ago. Thanks for taking our questions. In terms of Project Beagle and specifically the transition from Clarity C to Vivi, we really do not have much more to add to that. I think we had more than 25,000 patients that were using cash-pay Clarity C. We stopped making Clarity C in the summertime. I think largely those conversions have taken place. There are probably some units out in the field in various offices around the country. I expect for that to be kind of mopped up by the end of the year for sure. Those patients who will have transitioned to Vivi will have made that transition. In terms of TRIESENCE pricing, the pricing was at $944. You are moving into the ocular inflammation market. The products in that category are probably 20%–25% lower in price. I believe, and I think our team believes, that price would have affected adoption. In particular, as we focused on that ocular inflammation market, it was a good move, by the way. New orders are coming. As I said, it is not Mark talking about what might happen, what could happen. It is Mark talking about orders coming in, revenue, reorders. As I said in the stockholder letter, we have now confirmed reimbursement. You are talking about a product that has tremendous coverage, an extraordinarily low prior authorization rate, a multi-decade track record of performance. It is a product that is, I would say, beloved by ocular surgeons. There are a number of other reasons why, clinical reasons as well as economic reasons, why TRIESENCE is so exciting to these physicians that really did not know that this level of reimbursement was available for this product. We are seeing really positive things. I have been through this before. Our first product was a product called Trimoxy. It was a compounded combination of triamcinolone acetonide and moxifloxacin hydrochloride. I remember the adoption cycle there. What happens in the surgical environment in particular is you get a few cases, I tried to describe it in the letter as stockholders, and then they see that it performs terrific clinically. Now we've gone through the reimbursement cycle. There's really no reason why these physicians can't use this pervasively throughout their practice. There is this cycle to adoption. We're going through those cycles right now. What's really neat is once those physicians adopt this and it starts working so well for their patients and they see their patients coming in with clean white eyes on their post-op day one, they don't want to change. When they talk to their administrators at their surgery centers and they hear that they were reimbursed and they did not have to deal with prior authorization, they just do not want to change. It grows and grows and grows. At our peak with a non-FDA-approved compounded product, we were doing in excess of probably 300,000 units of Trimoxy and Trimoxy Venk years ago and some of these other sterile injectables. When I think about what TRIESENCE had done many years ago versus what we were doing with a non-FDA-approved product, which was significantly more than TRIESENCE in terms of annual unit volumes, I say that the units that we were doing with a non-FDA-approved product were minuscule relative to what the overall market opportunity is. I just wonder why any surgeon would not use TRIESENCE. We think that this is going to become hopefully the new standard of care for these patients. If it was my mother, if it was someone that I loved that was having a procedure and they could have the physician inject the medication to ensure that they had the medication on board and that they would not have to, as a 75, 78, 80-year-old patient with comorbidities, have to administer eye drops post-surgery, I think I would want my mother's physician to choose TRIESENCE. We think more and more physicians will. It's an exciting time for that product. We're just scratching the surface. I don't even know that you could even call it a scratch at this point. Absolute color, Mark. Thank you. Thank you. Our next question comes from Tom Shrader with BTIG. Your line is open. Good morning. Congratulations on the quarter. The TRIESENCE, that had a pretty good user base before, and we agree people loved the drug. Is it easy to move back into those people, or have they moved on? Could you just give us a sense of is that low-hanging fruit? Are those people waiting for the drug? You commented on fueling commercial operations for VEVYE. Does that mean adding conventional salespeople? If so, what other products do you think they could most easily help? Is TRIESENCE too far away for someone to market both VEVYE and TRIESENCE? Thanks. I do not want to keep talking, but if you do not mind, I am going to take both if that is all right. In terms of how easy it is to reengage and whether these physicians have moved on, when TRIESENCE was not available, without question, they moved on. They started using Kenalog, which has preservatives. It's got benzyl alcohol in it. If you're the patient, if the patient is someone you love, you don't want the doctor putting a chemical in their eye that could potentially blind them. That is why Alcon many years ago sought FDA approval for TRIESENCE because there was a clear unmet need in the marketplace for a preservative-free triamcinolone acetonide. That is TRIESENCE. That's what makes the product very special. If you knew that an iPhone 17 was not available, maybe you'd go back to the BlackBerry. Boy, as soon as you found out that the iPhone 17 was available, you're going to switch back. It does take time to reengage with these physicians. Many of them, even to this day, don't know that TRIESENCE is available, that it's in stock. They don't know about the low prior authorization rate, the reimbursement and coverage. That is our job. That is Chad's job. That is the job of this team that is going out, Aly and her folks and Adam, and really making it happen for this product. It takes time. I mean, you are talking about thousands and thousands of call points, but they are doing a great job. They are making progress. I think Pat talked about that. For Harrow and our stockholders, the juice will be worth a squeeze. I mean, this is a tremendous product. I have always said that I saw TRIESENCE as a nine-figure revenue product. I think we are going to get there in due course. You would not think that from the first quarter, the second quarter, and the third quarter. I think if we speak this time next year, you will see that I was not delusional. Finally, in terms of commercial ops for VEVYE, we're making those investments because we have coverage. When you have coverage, when you have the ability to have a prescription written and to get it filled in sort of a friction-free way. What we do know, by the way, and we've talked about this in prior stockholder letters, is that when we get a commercially covered VEVYE patient through our process, we retain them. Our refill rate is amazing for a commercially covered patient. Once we get that patient, now that we can get them covered, we can retain them because the product is so spectacular. It provides us with a sort of a compounding effect as we would get more new patients and retain them. You'll see that continued growth. In terms of other products that we're going to put in their bag, if you go through the corporate deck, one of the things I'm really excited about is we actually did add two products to the bag of our dry eye team. We have an amazing dry eye team. It will be growing. As I said, by the middle of next year, we'll have 100 territories. Maria's going to have a much larger group of folks to manage. They will also be helping patients and giving them access to Flarex. They'll have Freshco in their bag as well. The combination of a chronic care dry eye medication with other related products that cover ocular inflammation and Freshco in particular, which I think if you Google Freshco, you start looking at some of the marketing materials and its ability through polyvinyl alcohol base to actually help patients retain their tears and prevent evaporation. I think that's a really terrific product that the team is excited about. By the way, it's over the counter. I think you can get it for under $30 a unit. It's over the counter, so you don't need a prescription for it. We're going to do some exciting things with Freshco. Maria's got Flarex now. Of course, the cornerstone product in her portfolio is VEVYE Got it. Right. Thanks for the detail. Thank you, Tom. Thank you. Our next question comes from Lachlan Hanbury–Brown with William Blair. Your line is open. Hey, guys. Thanks for the questions. I guess I'd be curious on the new coverage for VEVYE. Can you just talk about how the economics there shake up or stack up compared to the current net pricing you're seeing? Because I know you've been sort of vocal, Mark, in the past about the economics that PBMs try to extract. It would be interesting to know just sort of where that shakes out. Also, once those new plans come online in 2026, what kind of coverage level are you looking at? What proportion of commercial lives nationally are covered for VEVYE? What I can tell you, and Andrew mentioned this, is that when you have a VAFA program and you establish a base, it takes you out of what we would call desperation mode to do bad deals with PBMs. Andrew, do you want to kind of add to that? You talked about it a little while earlier. Yeah. Without giving away the kind of bid, like Mark was saying, like I was saying, we kind of start with a base and we say, "Okay, if we're going to get a coverage win, what do we want? What does the economics need to be?" It obviously has to be an improvement on the cash number that we have. What that means and what I think, and without being specific about what that impact is going to be, the expectation is it's going to be an improvement for those patients over the cash price that we would net on a per-unit basis. We've talked a lot about just the ASP impact of the coverage win and that it'll help stabilize and certainly increase that number in 2026. There's another aspect to this, which is VEVYE was not preferred in this plan. Mark kind of talked about this. The fact that now it is preferred and another product got pulled out of that preferred status, the payer is letting the physicians know, "Hey, your patient was on this product and it's not going to be preferred next year, but VEVYE is." Not only are we going to get the increase in ASP, but just getting that preferred status, the PBM is helping us drive volume. You're going to kind of one begets the other, but it's going to be an increase in ASP. It should also be an increase in volume as well for the product. All right. Great. Thanks. Maybe a quick one on the VEVYE expansion, the new territory. Just to make sure I heard correctly, is that you're adding 10 new reps this quarter, and then we'll keep adding more until you get to about 100 next year, which, if I have my numbers right, is sort of roughly double where you're at now? Yeah. We're going to increase by 10. We'll get to a little bit more than 60 here in the very near term. By the second quarter, we'll hopefully have—we'll reach the century mark. We'll have about 100 territories. Awesome. Thanks. Thank you, Lachlan. Thank you. Our next question comes from Thomas Flaten with Lake Street Capital Markets. Your line is open. Hey, good morning. I appreciate you taking the questions. Hey, Mark, just to follow up, you mentioned the refill rates are great. Could you give us a sense of duration of therapy that some of these long-duration patients are on products for? I think last time that we looked at the data for a commercially covered patient, if you look at their initial prescription plus the refills and you add, you just think about the number of drops per bottle and the number of dosages per day. I mean, I think we were almost, we were right at these commercially covered patients getting therapy for the entirety of the year. I mean, I think it was only a few weeks away from, on average, refilling for the entirety of the year. I mean, we would have never, ever thought that we would get that sort of affinity of refill rate for that patient. I mean, that was not anywhere, even in the highest, the bullest of bull cases in our models. That's what we've seen. Andrew, you want to add to that at all? No, nothing else. Maybe if I could, bigger picture, you guys have been pretty busy on the BD front and have kind of created a really impressive to-do list for yourselves over the next couple of years. What should we anticipate in 2026, 2027? Is this more of an absorb, digest, and act, or is it more deals, more deals? Where do you land on that? I think at our office today and over the next week or so, we are over the moon excited about Melt. I don't think we've talked about Melt really at all, but we're hoping to get this closed here in the very near term. I don't think people really understand the value of Melt and what the potential is there. It's really transformative for us. Yeah, we look at deals constantly. We're always evaluating things. If you look at our portfolio and you think about some of the strategic goals that we've discussed and I've laid out even in the letter, in particular around cataract surgery, the vision for ophthalmic surgery that we have, which is to have opioid, IV, and drop-free cataract surgery, that's exciting for patients. That's transformative. The idea that you can probably go into an office, have office-based, maybe even bilateral same-day cataract surgery, and on the pharma side, have no IVs, no opioids, and not need eye drops post-surgery, that's extraordinary. That's what Melt and some of the other products that we have will enable. That's transformative for the nearly 5 million surgeries that occur annually in the US. We are looking at other deals. We're very interested in other deals. Right now, we're super pumped about Melt. We want to get that closed. We want to get the balance of the data collected and put into a dossier so that we can submit an NDA and get that product approved and help realize this vision that we have to really transform ophthalmic surgery. Eventually, hopefully see the Melt 300 drug candidate used outside of ophthalmology, which is really a much bigger market opportunity in dental and GI and claustrophobia for MRIs and the tens of millions of annual uses in the US where we think the Melt 300 will be impactful. Of course, what's also interesting is this will be the first global play that we have. Historically, we've been a US-focused business. As you, I think, know, Melt 300 is not only patented, multiple patents issued domestically, but in many of the major markets around the world. It is a global opportunity as well that we hope to discuss with partners and other markets around the world. Lots to look at, but I'll tell you, when we look at what we have with Melt and the products that we've acquired over the years recently, we have just something very, very special that we need to execute on. I'm really pleased to have Pat as my partner, our partner to help us do that. I appreciate that. Thanks, Mark. Thank you, Thomas. Thank you. Our next question comes from Yi Chen with HC Wainwright. Your line is open. Good morning. Thank you for taking my question. Mark, you mentioned that with the coverage wing, some prescriptions fled to VEVYE. Could you give some additional color on market dynamics, whether those prescriptions fled to VEVYE? They originally came from prescriptions for other cyclosporine formulations, or they could come from non-cyclosporine prescriptions as well. Thank you. Yeah. In terms of which product incurred the loss to our potential win, it was really, and I do not want to go into the specific products, but they were not cyclosporine-based products, but they were anti-inflammatories. You might be able to figure out which ones they were. In any case, for us, we are really focused on being the number one cyclosporine in the market. I think this really adds to that momentum. I think to be the number one cyclosporine in the market, you are talking about, I think with generics, probably 20-23% market share. We're at a little over 10. We do expect to see NPP improvement as we get more and more coverage and that ratio flips. This is going to really help us, I think, drive not only new prescriptions from patients naturally, but I think from these flips. As I said, I've seen the letters that have gone out to the eye care professionals. It lists the product that is no longer covered, and it lists the patients. I know from the few physicians that I've spoken to that their intention is to move them to VEVYE. However, I have to say, if you go around the country, there are many physicians in many markets all over the country that have no idea what VEVYE is. It is our job to make sure that they not only know about the clinical value that VEVYE brings, but also now the new coverage, which will, I think, create a more friction-free process for prescribing. Thank you. Thank you, Yi. Thank you. I'm sure no further questions. I'd like to turn the call back over to Mark L. Baum, CEO, for closing remarks. Thank you, operator. Thanks, everyone, for their questions. We really appreciate you joining us today. As we look into the future, I remain confident in where we're heading. We've built a solid foundation. We've brought together an outstanding leadership team and defined a clear strategy that touches every part of our business. We have a portfolio of best-in-class products and expanding access for patients and physicians and driving a culture that thrives on focus and execution. It positions Harrow for sustained growth and long-term value creation. The opportunities that we have ahead of us with TRIESENCE and VEVYE and IHEEZO are tremendous, and we are ready to capture them. If you have any further questions or you need additional information, please do not hesitate to reach out to Mike Biega. His email address is M as in Mary, B as in Bravo, I-E-G-A at harrowinc.com. This will conclude our call. Thank you for your participation. You may now disconnect. Good day.

Speaker 10: Good day, and welcome to the Harrow Third Quarter 2025 Earnings Conference Call. At this time, all participants are in a listen-only mode. After the speaker's presentation, there'll be a question-and-answer session. Instructions will be given at that time. As a reminder, this call may be recorded. I would like to turn the call over to Mike Biega, Vice President of Investor Relations and Communications. Please go ahead. Good day, and welcome to the Harrow Third Quarter 2025 Earnings Conference Call. good day and welcome to the harrow third quarter 2025 earnings conference call At this time, all participants are in a listen-only mode. at this time all participants are in a listen-only mode After the speaker's presentation, there'll be a question-and-answer session. after the speaker's presentation there'll be a question-and-answer session Instructions will be given at that time. instructions will be given at that time As a reminder, this call may be recorded. as a reminder this call may be recorded I would like to turn the call over to Mike Biega, Vice President of Investor Relations and Communications. i would like to turn the call over to mike biega vice president of investor relations and communications Please go ahead. please go ahead

Speaker 7: Thank you, Operator. Good morning, and welcome to Harrow's Third Quarter 2025 Earnings Conference Call. My name is Mike Biega, Vice President of Investor Relations and Communications, and I'm excited to be introducing today's call. Similar to our last quarterly call, we will be presenting slides during the webcast today. If you have registered and joined through the live conference call link, I would highly recommend that you also join through the webcast. You can find the link in the Investor section of our website at www.harrow.com or in our earnings press release that was issued yesterday. The company's remarks may include forward-looking statements within the meaning of federal securities laws. Thank you, Operator. thank you operator Good morning, and welcome to Harrow's Third Quarter 2025 Earnings Conference Call. good morning and welcome to harrow's third quarter 2025 earnings conference call My name is Mike Biega, Vice President of Investor Relations and Communications, and I'm excited to be introducing today's call. my name is mike biega vice president of investor relations and communications and i'm excited to be introducing today's call Similar to our last quarterly call, we will be presenting slides during the webcast today. similar to our last quarterly call we will be presenting slides during the webcast today If you have registered and joined through the live conference call link, I would highly recommend that you also join through the webcast. if you have registered and joined through the live conference call link i would highly recommend that you also join through the webcast You can find the link in the Investor section of our website at www.harrow.com or in our earnings press release that was issued yesterday. you can find the link in the investor section of our website at www.harrow.com or in our earnings press release that was issued yesterday The company's remarks may include forward-looking statements within the meaning of federal securities laws. the company's remarks may include forward-looking statements within the meaning of federal securities laws Forward-looking statements are subject to numerous risks and uncertainties, many of which are beyond Harrow's control, including risks and uncertainties described from time to time in its SEC filings, such as the risks and uncertainties related to the company's ability to make commercially available and FDA-approved products in compounded formulations and technology and FDA approval of certain drug candidates in a timely manner or at all. For a list and description of those risks and uncertainties, please see the Risk Factors section of the company's most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q filed with the Securities and Exchange Commission. Harrow's results may differ materially from those projected. Harrow disclaims any intention or obligation to update or revise any financial projections or forward-looking statements, whether because of new information, future events, or otherwise. Forward-looking statements are subject to numerous risks and uncertainties, many of which are beyond Harrow's control, including risks and uncertainties described from time to time in its SEC filings, such as the risks and uncertainties related to the company's ability to make commercially available and FDA-approved products in compounded formulations and technology and FDA approval of certain drug candidates in a timely manner or at all. forward-looking statements are subject to numerous risks and uncertainties many of which are beyond harrow's control including risks and uncertainties described from time to time in its sec filings such as the risks and uncertainties related to the company's ability to make commercially available and fda-approved products in compounded formulations and technology and fda approval of certain drug candidates in a timely manner or at all For a list and description of those risks and uncertainties, please see the Risk Factors section of the company's most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q filed with the Securities and Exchange Commission. for a list and description of those risks and uncertainties please see the risk factors section of the company's most recent annual report on form 10-k and subsequent quarterly reports on form 10-q filed with the securities and exchange commission Harrow's results may differ materially from those projected. harrow's results may differ materially from those projected Harrow disclaims any intention or obligation to update or revise any financial projections or forward-looking statements, whether because of new information, future events, or otherwise. harrow disclaims any intention or obligation to update or revise any financial projections or forward-looking statements whether because of new information future events or otherwise This conference call contains time-sensitive information and is accurate only as of today. Additionally, Harrow will refer to non-GAAP financial metrics, specifically adjusted EBITDA and/or adjusted earnings, as well as core results such as core gross margin, core net income, and core diluted net income per share. A reconciliation of any non-GAAP measures with the most directly comparable GAAP measures is included in the company's earnings release and letter to stockholders, both of which are available on the website. Now, joining me on today's call are Mark L. Baum, Chief Executive Officer; Andrew Boll, President and Chief Financial Officer; and Patrick Sullivan, Head of Commercial. With that, I would like to turn the call over to Mark. Mark? This conference call contains time-sensitive information and is accurate only as of today. this conference call contains time-sensitive information and is accurate only as of today Additionally, Harrow will refer to non-GAAP financial metrics, specifically adjusted EBITDA and/or adjusted earnings, as well as core results such as core gross margin, core net income, and core diluted net income per share. additionally harrow will refer to non-gaap financial metrics specifically adjusted ebitda and/or adjusted earnings as well as core results such as core gross margin core net income and core diluted net income per share A reconciliation of any non-GAAP measures with the most directly comparable GAAP measures is included in the company's earnings release and letter to stockholders, both of which are available on the website. a reconciliation of any non-gaap measures with the most directly comparable gaap measures is included in the company's earnings release and letter to stockholders both of which are available on the website Now, joining me on today's call are Mark L. now joining me on today's call are mark l Baum, Chief Executive Officer; Andrew Boll, President and Chief Financial Officer; and Patrick Sullivan, Head of Commercial. baum chief executive officer andrew boll president and chief financial officer and patrick sullivan head of commercial With that, I would like to turn the call over to Mark. with that i would like to turn the call over to mark Mark? mark

Speaker 13: Thanks, Mike, and good morning to everyone. Thanks for joining us today. As always, please review our supplemental documents for the third quarter, including our earnings release, corporate presentation, and letter to stockholders, all of which are now available on the Investor Relations section of our corporate website. During this call and in future quarterly conference calls, I'm pleased to have Pat Sullivan, Harrow's Head of Commercial, join us. Next quarter, I intend to have our Chief Scientific Officer, Amir Shojaei, join us as well. Today, Harrow is one of the leading providers of ophthalmic disease management solutions in North America. Our portfolio helps manage both front and back-of-the-eye conditions, and I believe we are the only ophthalmic company in the world to offer branded, generic, over-the-counter, compounded, and biosimilars, literally every legally available type of ophthalmic medication. Thanks, Mike, and good morning to everyone. thanks mike and good morning to everyone Thanks for joining us today. thanks for joining us today As always, please review our supplemental documents for the third quarter, including our earnings release, corporate presentation, and letter to stockholders, all of which are now available on the Investor Relations section of our corporate website. as always please review our supplemental documents for the third quarter including our earnings release corporate presentation and letter to stockholders all of which are now available on the investor relations section of our corporate website During this call and in future quarterly conference calls, I'm pleased to have Pat Sullivan, Harrow's Head of Commercial, join us. during this call and in future quarterly conference calls i'm pleased to have pat sullivan harrow's head of commercial join us Next quarter, I intend to have our Chief Scientific Officer, Amir Shojaei, join us as well. next quarter i intend to have our chief scientific officer amir shojaei join us as well Today, Harrow is one of the leading providers of ophthalmic disease management solutions in North America. today harrow is one of the leading providers of ophthalmic disease management solutions in north america Our portfolio helps manage both front and back-of-the-eye conditions, and I believe we are the only ophthalmic company in the world to offer branded, generic, over-the-counter, compounded, and biosimilars, literally every legally available type of ophthalmic medication. our portfolio helps manage both front and back-of-the-eye conditions and i believe we are the only ophthalmic company in the world to offer branded generic over-the-counter compounded and biosimilars literally every legally available type of ophthalmic medication At the center of everything we do is our vision to become the next great U.S. ophthalmic company. Now, 12 years into building this patient and physician-centric business, I believe we're still just getting started. Our key products are in their early stages of launch, with tremendous and durable growth ahead as adoption continues to accelerate. Over the next two years, we have four new product launches scheduled, each representing a significant opportunity to expand our reach, strengthen our leadership, and pave the way for even greater growth in the future. I am particularly proud of the fully scalable commercial infrastructure we've built, which will soon support multiple launches and continued expansion without requiring heavy additional investment. Combine that with a low-risk, capital-efficient pipeline development and M&A strategy, and it's clear Harrow's growth and market impact are in their infancy. At the center of everything we do is our vision to become the next great U.S. ophthalmic company. at the center of everything we do is our vision to become the next great u.s ophthalmic company Now, 12 years into building this patient and physician-centric business, I believe we're still just getting started. now 12 years into building this patient and physician-centric business i believe we're still just getting started Our key products are in their early stages of launch, with tremendous and durable growth ahead as adoption continues to accelerate. our key products are in their early stages of launch with tremendous and durable growth ahead as adoption continues to accelerate Over the next two years, we have four new product launches scheduled, each representing a significant opportunity to expand our reach, strengthen our leadership, and pave the way for even greater growth in the future. over the next two years we have four new product launches scheduled each representing a significant opportunity to expand our reach strengthen our leadership and pave the way for even greater growth in the future I am particularly proud of the fully scalable commercial infrastructure we've built, which will soon support multiple launches and continued expansion without requiring heavy additional investment. i am particularly proud of the fully scalable commercial infrastructure we've built which will soon support multiple launches and continued expansion without requiring heavy additional investment Combine that with a low-risk, capital-efficient pipeline development and M&A strategy, and it's clear Harrow's growth and market impact are in their infancy. combine that with a low-risk capital-efficient pipeline development and m&a strategy and it's clear harrow's growth and market impact are in their infancy Now, our momentum continued during the third quarter with rising revenue and clear evidence of the operating leverage in our business model. As I've mentioned before, some areas of our business will overperform, while others may lag, sometimes due to seasonal factors, and the third quarter was no exception. What matters most, though, is the overall trajectory of the business, and that trajectory remains very strong. Our key growth engines, such as VEVYE, IHEEZO, and, to a certain extent, beginning very recently, TRIESENCE, are rolling, and momentum continues to build across the business, especially as we approach the launch of the Samsung Bioepis biosimilar portfolio and conclude the acquisition of Melt Pharmaceuticals, which I'm very excited about. Now, VEVYE and IHEEZO continue to lead the way and are on track to finish the year very strong. In fact, 2025 is expected to be a record year for both products. Now, our momentum continued during the third quarter with rising revenue and clear evidence of the operating leverage in our business model. now our momentum continued during the third quarter with rising revenue and clear evidence of the operating leverage in our business model As I've mentioned before, some areas of our business will overperform, while others may lag, sometimes due to seasonal factors, and the third quarter was no exception. as i've mentioned before some areas of our business will overperform while others may lag sometimes due to seasonal factors and the third quarter was no exception What matters most, though, is the overall trajectory of the business, and that trajectory remains very strong. what matters most though is the overall trajectory of the business and that trajectory remains very strong Our key growth engines, such as VEVYE, IHEEZO, and, to a certain extent, beginning very recently, TRIESENCE, are rolling, and momentum continues to build across the business, especially as we approach the launch of the Samsung Bioepis biosimilar portfolio and conclude the acquisition of Melt Pharmaceuticals, which I'm very excited about. our key growth engines such as vevye iheezo and to a certain extent beginning very recently triesence are rolling and momentum continues to build across the business especially as we approach the launch of the samsung bioepis biosimilar portfolio and conclude the acquisition of melt pharmaceuticals which i'm very excited about Now, VEVYE and IHEEZO continue to lead the way and are on track to finish the year very strong. now vevye and iheezo continue to lead the way and are on track to finish the year very strong In fact, 2025 is expected to be a record year for both products. in fact 2025 is expected to be a record year for both products They've shown consistent momentum and continue to drive the majority of our growth. Driven by strong demand and best-in-class clinical performance, VEVYE delivered 22% quarter-over-quarter revenue growth. Perhaps a key highlight of my remarks, though, should be the news that we have recently signed agreements with several leading national payers for VEVYE. Beginning in January 2026, only a couple of months away, VEVYE will be listed on multiple new formularies with a preferred product status, including the largest U.S. Pharmacy Benefit Manager. This means that certain products are becoming uncovered, and that creates an opportunity for prescription transfers. Going forward, VEVYE will be covered on those formularies. This particular PBM covers tens of millions of lives, and I view this as a major development for VEVYE and for Harrow. They've shown consistent momentum and continue to drive the majority of our growth. they've shown consistent momentum and continue to drive the majority of our growth Driven by strong demand and best-in-class clinical performance, VEVYE delivered 22% quarter-over-quarter revenue growth. driven by strong demand and best-in-class clinical performance vevye delivered 22% quarter-over-quarter revenue growth Perhaps a key highlight of my remarks, though, should be the news that we have recently signed agreements with several leading national payers for VEVYE. perhaps a key highlight of my remarks though should be the news that we have recently signed agreements with several leading national payers for vevye Beginning in January 2026, only a couple of months away, VEVYE will be listed on multiple new formularies with a preferred product status, including the largest U.S. beginning in january 2026 only a couple of months away vevye will be listed on multiple new formularies with a preferred product status including the largest u.s Pharmacy Benefit Manager. pharmacy benefit manager This means that certain products are becoming uncovered, and that creates an opportunity for prescription transfers. this means that certain products are becoming uncovered and that creates an opportunity for prescription transfers Going forward, VEVYE will be covered on those formularies. going forward vevye will be covered on those formularies This particular PBM covers tens of millions of lives, and I view this as a major development for VEVYE and for Harrow. this particular pbm covers tens of millions of lives and i view this as a major development for vevye and for harrow With major improvements in coverage and the addition of ApolloCare and Alto joining our specialty pharmacy network this quarter, we expect a higher proportion of patients will receive VEVYE as a covered therapy. These advancements strengthen VEVYE's market access foundation and fuel continued prescription growth, resulting in an improved ratio of covered to cash pay prescriptions. This includes estimates of current cash pay patients who are likely to convert to covered prescriptions, and that gives us confidence in VEVYE's pricing stability and long-term growth. IHEEZO also had an excellent quarter, delivering 20% quarter-over-quarter revenue growth. That's an impressive performance given the typical seasonal slowdown for that product in the third quarter. Meanwhile, TRIESENCE and our rare and specialty portfolio underperformed this year, as I talk more about in our stockholder letter, and that also included the third quarter. With major improvements in coverage and the addition of ApolloCare and Alto joining our specialty pharmacy network this quarter, we expect a higher proportion of patients will receive VEVYE as a covered therapy. with major improvements in coverage and the addition of apollocare and alto joining our specialty pharmacy network this quarter we expect a higher proportion of patients will receive vevye as a covered therapy These advancements strengthen VEVYE's market access foundation and fuel continued prescription growth, resulting in an improved ratio of covered to cash pay prescriptions. these advancements strengthen vevye's market access foundation and fuel continued prescription growth resulting in an improved ratio of covered to cash pay prescriptions This includes estimates of current cash pay patients who are likely to convert to covered prescriptions, and that gives us confidence in VEVYE's pricing stability and long-term growth. this includes estimates of current cash pay patients who are likely to convert to covered prescriptions and that gives us confidence in vevye's pricing stability and long-term growth IHEEZO also had an excellent quarter, delivering 20% quarter-over-quarter revenue growth. iheezo also had an excellent quarter delivering 20% quarter-over-quarter revenue growth That's an impressive performance given the typical seasonal slowdown for that product in the third quarter. that's an impressive performance given the typical seasonal slowdown for that product in the third quarter Meanwhile, TRIESENCE and our rare and specialty portfolio underperformed this year, as I talk more about in our stockholder letter, and that also included the third quarter. meanwhile triesence and our rare and specialty portfolio underperformed this year as i talk more about in our stockholder letter and that also included the third quarter The good news, though, is that we have the right leadership and strategies in place, I believe, to get both on track in short order. TRIESENCE, in particular, is gaining traction in retina, and as of October of this year, we launched it in its largest market opportunity yet, ocular inflammation. Our rare and specialty portfolio also has new leadership, and they are supporting our Harrow Access for All program, which is positioned to return this portfolio to growth beginning in the fourth quarter and into 2026. Please review the letter to stockholders for more specific thoughts, though, on TRIESENCE and our rare and specialty products portfolio. We also made important strategic moves this quarter as we worked to complete the acquisition of Melt Pharmaceuticals and its non-opioid procedural sedation candidate, Melt 300, and we also expanded our Access for All model across our entire ophthalmic portfolio. The good news, though, is that we have the right leadership and strategies in place, I believe, to get both on track in short order. the good news though is that we have the right leadership and strategies in place i believe to get both on track in short order TRIESENCE, in particular, is gaining traction in retina, and as of October of this year, we launched it in its largest market opportunity yet, ocular inflammation. triesence in particular is gaining traction in retina and as of october of this year we launched it in its largest market opportunity yet ocular inflammation Our rare and specialty portfolio also has new leadership, and they are supporting our Harrow Access for All program, which is positioned to return this portfolio to growth beginning in the fourth quarter and into 2026. our rare and specialty portfolio also has new leadership and they are supporting our harrow access for all program which is positioned to return this portfolio to growth beginning in the fourth quarter and into 2026 Please review the letter to stockholders for more specific thoughts, though, on TRIESENCE and our rare and specialty products portfolio. please review the letter to stockholders for more specific thoughts though on triesence and our rare and specialty products portfolio We also made important strategic moves this quarter as we worked to complete the acquisition of Melt Pharmaceuticals and its non-opioid procedural sedation candidate, Melt 300, and we also expanded our Access for All model across our entire ophthalmic portfolio. we also made important strategic moves this quarter as we worked to complete the acquisition of melt pharmaceuticals and its non-opioid procedural sedation candidate melt 300 and we also expanded our access for all model across our entire ophthalmic portfolio We're also preparing for four product launches over the next three years: BioViz, OpioViz, Biclovi, and Melt 300, which I'm particularly excited about. In short, our strategy is bearing fruit. We're executing with discipline, scaling with purpose, and building a company defined by innovation, access, and sustainable growth, creating meaningful long-term value for both patients and shareholders. Before I hand it over to Andrew, I want to take a moment to address our ImprimisRx business in California, where, as many of you know, we have been engaged in a dispute with the California Board of Pharmacy for many years. ImprimisRx remains licensed to operate in California, but its license is up for renewal on December 1, 2025. We are actively communicating with the California Board towards a global resolution, which would include a renewal of our license. We're also preparing for four product launches over the next three years: BioViz, OpioViz, Biclovi, and Melt 300, which I'm particularly excited about. we're also preparing for four product launches over the next three years bioviz opioviz biclovi and melt 300 which i'm particularly excited about In short, our strategy is bearing fruit. in short our strategy is bearing fruit We're executing with discipline, scaling with purpose, and building a company defined by innovation, access, and sustainable growth, creating meaningful long-term value for both patients and shareholders. we're executing with discipline scaling with purpose and building a company defined by innovation access and sustainable growth creating meaningful long-term value for both patients and shareholders Before I hand it over to Andrew, I want to take a moment to address our ImprimisRx business in California, where, as many of you know, we have been engaged in a dispute with the California Board of Pharmacy for many years. before i hand it over to andrew i want to take a moment to address our imprimisrx business in california where as many of you know we have been engaged in a dispute with the california board of pharmacy for many years ImprimisRx remains licensed to operate in California, but its license is up for renewal on December 1, 2025. imprimisrx remains licensed to operate in california but its license is up for renewal on december 1 2025 We are actively communicating with the California Board towards a global resolution, which would include a renewal of our license. we are actively communicating with the california board towards a global resolution which would include a renewal of our license Because these discussions are ongoing and, frankly, no outcome can be certain, I can't comment on other specific details, but this is top of mind for us, and we believe a solution may be at hand. As more information becomes available, we will communicate with our stockholders. With that, I would like to now turn it over to our President and Chief Financial Officer, Andrew Boll. Andrew? Because these discussions are ongoing and, frankly, no outcome can be certain, I can't comment on other specific details, but this is top of mind for us, and we believe a solution may be at hand. because these discussions are ongoing and frankly no outcome can be certain i can't comment on other specific details but this is top of mind for us and we believe a solution may be at hand As more information becomes available, we will communicate with our stockholders. as more information becomes available we will communicate with our stockholders With that, I would like to now turn it over to our President and Chief Financial Officer, Andrew Boll. with that i would like to now turn it over to our president and chief financial officer andrew boll Andrew? andrew

Speaker 3: Thanks, Mark, and thank you to everyone joining the call today. Turning now to our financial performance, total revenue for the third quarter was $71.6 million, representing a 45% increase over the same period in 2024 and a 12% sequential increase from the second quarter of this year. For the first nine months of 2025, total revenue reached $183.2 million. We remain firmly on track for another strong year of revenue growth, advancing toward our long-term financial targets with disciplined execution. Based on what we're seeing across the business today, which I'll walk through in greater detail in the next slide, we are updating our full-year revenue outlook to a range of $270-$280 million. While hitting our original target of over $280 million is still within reach, we want to take a slightly more conservative approach and update guidance for a range we believe we can deliver on. Thanks, Mark, and thank you to everyone joining the call today. thanks mark and thank you to everyone joining the call today Turning now to our financial performance, total revenue for the third quarter was $71.6 million, representing a 45% increase over the same period in 2024 and a 12% sequential increase from the second quarter of this year. turning now to our financial performance total revenue for the third quarter was $71.6 million representing a 45% increase over the same period in 2024 and a 12% sequential increase from the second quarter of this year For the first nine months of 2025, total revenue reached $183.2 million. for the first nine months of 2025 total revenue reached $183.2 million We remain firmly on track for another strong year of revenue growth, advancing toward our long-term financial targets with disciplined execution. we remain firmly on track for another strong year of revenue growth advancing toward our long-term financial targets with disciplined execution Based on what we're seeing across the business today, which I'll walk through in greater detail in the next slide, we are updating our full-year revenue outlook to a range of $270-$280 million. based on what we're seeing across the business today which i'll walk through in greater detail in the next slide we are updating our full-year revenue outlook to a range of $270-$280 million While hitting our original target of over $280 million is still within reach, we want to take a slightly more conservative approach and update guidance for a range we believe we can deliver on. while hitting our original target of over $280 million is still within reach we want to take a slightly more conservative approach and update guidance for a range we believe we can deliver on Adjusted EBITDA for the third quarter was $22.7 million, with GAAP-based net income of $1 million. Operating expenses continue to be relatively stable quarter to quarter, and we are seeing more operating leverage manifest itself within the new revenue gains. As we continue to scale, our ability to translate revenue growth into earnings remains a core strength of Harrow's model. As we advance into the fourth quarter, we expect to see operating expenses moderately increase as further investments are made in our commercial infrastructure to accelerate sales, and that trend should continue into 2026. Let's turn to our product performance. VEVYE continues to outperform, generating approximately $22.6 million in revenue during the third quarter. This is a 22% increase from the second quarter of 2025. This revenue increase was driven on continued increase in unit volumes year-over-year and quarter-over-quarter. Adjusted EBITDA for the third quarter was $22.7 million, with GAAP-based net income of $1 million. adjusted ebitda for the third quarter was $22.7 million with gaap-based net income of $1 million Operating expenses continue to be relatively stable quarter to quarter, and we are seeing more operating leverage manifest itself within the new revenue gains. operating expenses continue to be relatively stable quarter to quarter and we are seeing more operating leverage manifest itself within the new revenue gains As we continue to scale, our ability to translate revenue growth into earnings remains a core strength of Harrow's model. as we continue to scale our ability to translate revenue growth into earnings remains a core strength of harrow's model As we advance into the fourth quarter, we expect to see operating expenses moderately increase as further investments are made in our commercial infrastructure to accelerate sales, and that trend should continue into 2026. as we advance into the fourth quarter we expect to see operating expenses moderately increase as further investments are made in our commercial infrastructure to accelerate sales and that trend should continue into 2026 Let's turn to our product performance. let's turn to our product performance VEVYE continues to outperform, generating approximately $22.6 million in revenue during the third quarter. vevye continues to outperform generating approximately $22.6 million in revenue during the third quarter This is a 22% increase from the second quarter of 2025. this is a 22% increase from the second quarter of 2025 This revenue increase was driven on continued increase in unit volumes year-over-year and quarter-over-quarter. this revenue increase was driven on continued increase in unit volumes year-over-year and quarter-over-quarter VEVYE is set up for a record fourth quarter. October hit an all-time high in prescriptions, and that momentum has carried right through the first week of November. Q4 was VEVYE's strongest period last year, and with the trends we're seeing, I'm confident we're on track to finish near our $100 million annual revenue target for 2025, with additional meaningful growth expected in 2026 as improved coverage kicks in and we further invest into VEVYE's commercial infrastructure to fuel the next phase of growth. Turning to IHEEZO, revenue for the third quarter came in at $21.9 million. This is up 20% from the second quarter. As we've seen in prior years, the third quarter tends to be seasonally softer due to the July and August slowdown as both patients and physicians take time off. That said, demand rebounded sharply in September and remained strong through October. VEVYE is set up for a record fourth quarter. vevye is set up for a record fourth quarter October hit an all-time high in prescriptions, and that momentum has carried right through the first week of November. october hit an all-time high in prescriptions and that momentum has carried right through the first week of november Q4 was VEVYE's strongest period last year, and with the trends we're seeing, I'm confident we're on track to finish near our $100 million annual revenue target for 2025, with additional meaningful growth expected in 2026 as improved coverage kicks in and we further invest into VEVYE's commercial infrastructure to fuel the next phase of growth. q4 was vevye's strongest period last year and with the trends we're seeing i'm confident we're on track to finish near our $100 million annual revenue target for 2025 with additional meaningful growth expected in 2026 as improved coverage kicks in and we further invest into vevye's commercial infrastructure to fuel the next phase of growth Turning to IHEEZO, revenue for the third quarter came in at $21.9 million. turning to iheezo revenue for the third quarter came in at $21.9 million This is up 20% from the second quarter. this is up 20% from the second quarter As we've seen in prior years, the third quarter tends to be seasonally softer due to the July and August slowdown as both patients and physicians take time off. as we've seen in prior years the third quarter tends to be seasonally softer due to the july and august slowdown as both patients and physicians take time off That said, demand rebounded sharply in September and remained strong through October. that said demand rebounded sharply in september and remained strong through october IHEEZO has significantly outperformed our expectations this year and is also on track for a very strong fourth quarter and a record year. The fourth quarter has historically been IHEEZO's highest volume quarter, supported by end-of-year ordering patterns and stocking activity, and we've already seen large orders placed early in the period. Based on those dynamics, we expect IHEEZO to deliver a strong close to 2025. Our TRIESENCE and broader specialty branded portfolio generated $6.9 million in revenue. This is a 33% sequential increase. As Mark discussed and highlighted in our letter to stockholders, with new leadership in place, a dedicated sales force, the launch of Harrow Access for All, and TRIESENCE's launch into ocular inflammation, we now have the focus and strategies in place to reignite growth, starting as early as the fourth quarter of this year. IHEEZO has significantly outperformed our expectations this year and is also on track for a very strong fourth quarter and a record year. iheezo has significantly outperformed our expectations this year and is also on track for a very strong fourth quarter and a record year The fourth quarter has historically been IHEEZO's highest volume quarter, supported by end-of-year ordering patterns and stocking activity, and we've already seen large orders placed early in the period. the fourth quarter has historically been iheezo's highest volume quarter supported by end-of-year ordering patterns and stocking activity and we've already seen large orders placed early in the period Based on those dynamics, we expect IHEEZO to deliver a strong close to 2025. based on those dynamics we expect iheezo to deliver a strong close to 2025 Our TRIESENCE and broader specialty branded portfolio generated $6.9 million in revenue. our triesence and broader specialty branded portfolio generated $6.9 million in revenue This is a 33% sequential increase. this is a 33% sequential increase As Mark discussed and highlighted in our letter to stockholders, with new leadership in place, a dedicated sales force, the launch of Harrow Access for All, and TRIESENCE's launch into ocular inflammation, we now have the focus and strategies in place to reignite growth, starting as early as the fourth quarter of this year. as mark discussed and highlighted in our letter to stockholders with new leadership in place a dedicated sales force the launch of harrow access for all and triesence's launch into ocular inflammation we now have the focus and strategies in place to reignite growth starting as early as the fourth quarter of this year ImprimisRx products continue to provide stable recurring revenue, generating approximately $20.1 million in revenue in the third quarter. As Mark mentioned earlier, if we are unable to resolve the dispute with the California Board of Pharmacy, we may see a minor impact on ImprimisRx's fourth quarter revenue. In addition, ImprimisRx had an inventory shortage during the month of October, causing a one-time decrease of about $4–$6 million in its revenue for the fourth quarter. In summary, we are fully focused on achieving our third consecutive year of 40% or higher annual revenue growth, with all hands on deck across the organization. VEVYE and IHEEZO are both positioned for a strong finish to the year and a record quarter. However, given the certain near-term factors, we're updating our full-year outlook to a range of $270–$280 million. ImprimisRx products continue to provide stable recurring revenue, generating approximately $20.1 million in revenue in the third quarter. imprimisrx products continue to provide stable recurring revenue generating approximately $20.1 million in revenue in the third quarter As Mark mentioned earlier, if we are unable to resolve the dispute with the California Board of Pharmacy, we may see a minor impact on ImprimisRx's fourth quarter revenue. as mark mentioned earlier if we are unable to resolve the dispute with the california board of pharmacy we may see a minor impact on imprimisrx's fourth quarter revenue In addition, ImprimisRx had an inventory shortage during the month of October, causing a one-time decrease of about $4–$6 million in its revenue for the fourth quarter. in addition imprimisrx had an inventory shortage during the month of october causing a one-time decrease of about $4–$6 million in its revenue for the fourth quarter In summary, we are fully focused on achieving our third consecutive year of 40% or higher annual revenue growth, with all hands on deck across the organization. in summary we are fully focused on achieving our third consecutive year of 40% or higher annual revenue growth with all hands on deck across the organization VEVYE and IHEEZO are both positioned for a strong finish to the year and a record quarter. vevye and iheezo are both positioned for a strong finish to the year and a record quarter However, given the certain near-term factors, we're updating our full-year outlook to a range of $270–$280 million. however given the certain near-term factors we're updating our full-year outlook to a range of $270–$280 million While our original target is still within reach, this new range is a one I believe we can deliver on based on where we are today. That said, the fundamentals of our business remain strong, and I could be more confident in the long-term growth trajectory. Looking ahead, following what we expect to be a strong fourth quarter, we anticipate a typical seasonal decline from Q4 2025–Q1 2026, likely consistent with the pattern we saw earlier this year. This does not mean that we will not achieve record results next year, which is what we expect to happen. However, we want to establish that Q1 presents a seasonality that we need to consider. I will provide more color on the magnitude of that dynamic when we report full-year results, including the expected impact from the fourth quarter stocking activities. While our original target is still within reach, this new range is a one I believe we can deliver on based on where we are today. while our original target is still within reach this new range is a one i believe we can deliver on based on where we are today That said, the fundamentals of our business remain strong, and I could be more confident in the long-term growth trajectory. that said the fundamentals of our business remain strong and i could be more confident in the long-term growth trajectory Looking ahead, following what we expect to be a strong fourth quarter, we anticipate a typical seasonal decline from Q4 2025 – Q1 2026, likely consistent with the pattern we saw earlier this year. looking ahead following what we expect to be a strong fourth quarter we anticipate a typical seasonal decline from q4 2025 – q1 2026 likely consistent with the pattern we saw earlier this year This does not mean that we will not achieve record results next year, which is what we expect to happen. this does not mean that we will not achieve record results next year which is what we expect to happen However, we want to establish that Q1 presents a seasonality that we need to consider. I will provide more color on the magnitude of that dynamic when we report full-year results, including the expected impact from the fourth quarter stocking activities. however we want to establish that q1 presents a seasonality that we need to consider. i will provide more color on the magnitude of that dynamic when we report full-year results including the expected impact from the fourth quarter stocking activities

Speaker 12: Thanks, Andrew. My responsibility as Harrow's commercial leader is crystal clear: unlock the massive commercial potential in our portfolio and position Harrow for sustained, profitable growth. As many of you know, I've been in this role for less than six months, but I am not new to commercial leadership, building successful teams to execute thoughtful strategies and ultimately delivering extraordinary results. I would like to highlight the five commercial priorities that will drive my team's efforts. First, we're activating our advanced key account management initiative. This is about deepening relationships with high-value accounts, fueling trial, accelerating adoption, and building long-term loyalty across the brands. Second, we're elevating our focus on driving depth and breadth, expanding our reach to more prescribers and new accounts while going deeper within existing users. This is key to unlocking the full potential of our portfolio. Thanks, Andrew. thanks andrew My responsibility as Harrow's commercial leader is crystal clear: unlock the massive commercial potential in our portfolio and position Harrow for sustained, profitable growth. my responsibility as harrow's commercial leader is crystal clear unlock the massive commercial potential in our portfolio and position harrow for sustained profitable growth As many of you know, I've been in this role for less than six months, but I am not new to commercial leadership, building successful teams to execute thoughtful strategies and ultimately delivering extraordinary results. as many of you know i've been in this role for less than six months but i am not new to commercial leadership building successful teams to execute thoughtful strategies and ultimately delivering extraordinary results I would like to highlight the five commercial priorities that will drive my team's efforts. i would like to highlight the five commercial priorities that will drive my team's efforts First, we're activating our advanced key account management initiative. first we're activating our advanced key account management initiative This is about deepening relationships with high-value accounts, fueling trial, accelerating adoption, and building long-term loyalty across the brands. this is about deepening relationships with high-value accounts fueling trial accelerating adoption and building long-term loyalty across the brands Second, we're elevating our focus on driving depth and breadth, expanding our reach to more prescribers and new accounts while going deeper within existing users. second we're elevating our focus on driving depth and breadth expanding our reach to more prescribers and new accounts while going deeper within existing users This is key to unlocking the full potential of our portfolio. this is key to unlocking the full potential of our portfolio Third, we have a scalable investment model across the commercial organization, one that allows us to grow efficiently, invest intelligently, and maximize return on every dollar spent. Fourth, we're expanding awareness of our Harrow Access Solutions program to ensure a smooth and positive experience for both eye care professionals and their patients. Removing barriers to access remains a cornerstone of our strategy. Finally, we're sustaining operational discipline and stability, maintaining an efficient cost base while continuing to execute at a high level. These commercial acceleration priorities position us to drive stronger adoption, profitable growth, and continue our journey as an emerging leader in the ophthalmic market. VEVYE continued to strengthen and expand its position in the dry eye market during the third quarter, delivering strong and sustained growth. Our commercial strategy is working. We're seeing increasing physician confidence, excellent patient outcomes, and faster, more affordable access to therapy. Third, we have a scalable investment model across the commercial organization, one that allows us to grow efficiently, invest intelligently, and maximize return on every dollar spent. third we have a scalable investment model across the commercial organization one that allows us to grow efficiently invest intelligently and maximize return on every dollar spent Fourth, we're expanding awareness of our Harrow Access Solutions program to ensure a smooth and positive experience for both eye care professionals and their patients. fourth we're expanding awareness of our harrow access solutions program to ensure a smooth and positive experience for both eye care professionals and their patients Removing barriers to access remains a cornerstone of our strategy. removing barriers to access remains a cornerstone of our strategy Finally, we're sustaining operational discipline and stability, maintaining an efficient cost base while continuing to execute at a high level. finally we're sustaining operational discipline and stability maintaining an efficient cost base while continuing to execute at a high level These commercial acceleration priorities position us to drive stronger adoption, profitable growth, and continue our journey as an emerging leader in the ophthalmic market. these commercial acceleration priorities position us to drive stronger adoption profitable growth and continue our journey as an emerging leader in the ophthalmic market VEVYE continued to strengthen and expand its position in the dry eye market during the third quarter, delivering strong and sustained growth. vevye continued to strengthen and expand its position in the dry eye market during the third quarter delivering strong and sustained growth Our commercial strategy is working. our commercial strategy is working We're seeing increasing physician confidence, excellent patient outcomes, and faster, more affordable access to therapy. we're seeing increasing physician confidence excellent patient outcomes and faster more affordable access to therapy By the end of September, we saw a 36% increase in prescribing physicians, a strong indicator of continued growth and expanding physician adoption. Our VEVYE Access for All initiative remains a key enabler of growth for VEVYE, simplifying the patient experience and fueling demand. Starting in January, VEVYE will appear on several new national formularies with preferred status, including the largest Pharmacy Benefit Manager in the United States. VEVYE's improving coverage serves as another catalyst to expand utilization among eye care physicians and among more patients with dry eye disease. We anticipate that these increased coverage wins. Many current cash-pay patients will take advantage of VEVYE's improved coverage in their plans. We also expanded our specialty pharmacy network. PhilRx handled all prescriptions in Q3, while ApolloCare went live in Q4, and AltoRx will follow later this quarter. Steps to further improve patient access for patients. By the end of September, we saw a 36% increase in prescribing physicians, a strong indicator of continued growth and expanding physician adoption. by the end of september we saw a 36% increase in prescribing physicians a strong indicator of continued growth and expanding physician adoption Our VEVYE Access for All initiative remains a key enabler of growth for VEVYE, simplifying the patient experience and fueling demand. our vevye access for all initiative remains a key enabler of growth for vevye simplifying the patient experience and fueling demand Starting in January, VEVYE will appear on several new national formularies with preferred status, including the largest Pharmacy Benefit Manager in the United States. starting in january vevye will appear on several new national formularies with preferred status including the largest pharmacy benefit manager in the united states VEVYE's improving coverage serves as another catalyst to expand utilization among eye care physicians and among more patients with dry eye disease. vevye's improving coverage serves as another catalyst to expand utilization among eye care physicians and among more patients with dry eye disease We anticipate that these increased coverage wins. we anticipate that these increased coverage wins Many current cash-pay patients will take advantage of VEVYE's improved coverage in their plans. many current cash-pay patients will take advantage of vevye's improved coverage in their plans We also expanded our specialty pharmacy network. we also expanded our specialty pharmacy network PhilRx handled all prescriptions in Q3, while ApolloCare went live in Q4, and AltoRx will follow later this quarter. philrx handled all prescriptions in q3 while apollocare went live in q4 and altorx will follow later this quarter Steps to further improve patient access for patients. steps to further improve patient access for patients Combined with the broader payer coverage coming in 2026, these developments favorably position VEVYE for continued growth and pricing stability. Let's look at VEVYE's outlook. Looking at the chart on the top left, the picture is clear. The dry eye disease market is large, active, and growing. The branded segment is the key driver for growth in the overall market. By the end of the third quarter, VEVYE captured 10.5% of the total dry eye market, up 2.7 share points from the prior quarter, effectively doubling its market share in just two quarters. It's a clear sign of strong, sustained growth and proof that our strategy is delivering results. Our goal remains the same: to make VEVYE the number one prescribed cyclosporine therapy in the U.S., and we're making steady progress toward that. Combined with the broader payer coverage coming in 2026, these developments favorably position VEVYE for continued growth and pricing stability. combined with the broader payer coverage coming in 2026 these developments favorably position vevye for continued growth and pricing stability Let's look at VEVYE's outlook. let's look at vevye's outlook Looking at the chart on the top left, the picture is clear. looking at the chart on the top left the picture is clear The dry eye disease market is large, active, and growing. the dry eye disease market is large active and growing The branded segment is the key driver for growth in the overall market. the branded segment is the key driver for growth in the overall market By the end of the third quarter, VEVYE captured 10.5% of the total dry eye market, up 2.7 share points from the prior quarter, effectively doubling its market share in just two quarters. by the end of the third quarter vevye captured 10.5% of the total dry eye market up 2.7 share points from the prior quarter effectively doubling its market share in just two quarters It's a clear sign of strong, sustained growth and proof that our strategy is delivering results. it's a clear sign of strong sustained growth and proof that our strategy is delivering results Our goal remains the same: to make VEVYE the number one prescribed cyclosporine therapy in the U.S., and we're making steady progress toward that. our goal remains the same to make vevye the number one prescribed cyclosporine therapy in the u.s and we're making steady progress toward that We're building momentum every quarter, increasing adoption, improving access, and expanding coverage, and we remain confident in our path to becoming the leading cyclosporine therapy in the dry eye space. Looking ahead, we're focused on accelerating growth through both depth and breadth, deepening utilization with existing eye care physicians while expanding use among new physicians and their patients. Now that we are comfortable with our supply, we are also preparing for the next phase of expansion with plans to invest in VEVYE's commercial infrastructure and open 10 additional sales territories to fuel the next phase of growth. We anticipate that more territories will open during the first half of 2026, and we are going to focus on markets served by the new plans that will cover VEVYE. The momentum behind VEVYE is clear. We're building momentum every quarter, increasing adoption, improving access, and expanding coverage, and we remain confident in our path to becoming the leading cyclosporine therapy in the dry eye space. we're building momentum every quarter increasing adoption improving access and expanding coverage and we remain confident in our path to becoming the leading cyclosporine therapy in the dry eye space Looking ahead, we're focused on accelerating growth through both depth and breadth, deepening utilization with existing eye care physicians while expanding use among new physicians and their patients. looking ahead we're focused on accelerating growth through both depth and breadth deepening utilization with existing eye care physicians while expanding use among new physicians and their patients Now that we are comfortable with our supply, we are also preparing for the next phase of expansion with plans to invest in VEVYE's commercial infrastructure and open 10 additional sales territories to fuel the next phase of growth. now that we are comfortable with our supply we are also preparing for the next phase of expansion with plans to invest in vevye's commercial infrastructure and open 10 additional sales territories to fuel the next phase of growth We anticipate that more territories will open during the first half of 2026, and we are going to focus on markets served by the new plans that will cover VEVYE. we anticipate that more territories will open during the first half of 2026 and we are going to focus on markets served by the new plans that will cover vevye The momentum behind VEVYE is clear. the momentum behind vevye is clear With growing adoption, strong clinical outcomes, a patient-centric access model, and improving coverage, we're just getting started. VEVYE has doubled its market share over the past two quarters, and with new investments in our commercial infrastructure to support the next phase of expansion, the opportunity ahead is tremendous. I'm confident our team is fully aligned and focused on making VEVYE the new standard of care for dry eye disease. Let's look at IHEEZO. IHEEZO had another excellent quarter. Unit demand was up 47% from last year and 3% sequentially. That's strong, sustained growth, and continued proof that IHEEZO's value proposition is resonating in the market. As expected, the third quarter followed normal seasonality. A brief slowdown in July and August, but demand rebounded quickly in September and continued through October. With growing adoption, strong clinical outcomes, a patient-centric access model, and improving coverage, we're just getting started. with growing adoption strong clinical outcomes a patient-centric access model and improving coverage we're just getting started VEVYE has doubled its market share over the past two quarters, and with new investments in our commercial infrastructure to support the next phase of expansion, the opportunity ahead is tremendous. vevye has doubled its market share over the past two quarters and with new investments in our commercial infrastructure to support the next phase of expansion the opportunity ahead is tremendous I'm confident our team is fully aligned and focused on making VEVYE the new standard of care for dry eye disease. i'm confident our team is fully aligned and focused on making vevye the new standard of care for dry eye disease Let's look at IHEEZO. let's look at iheezo IHEEZO had another excellent quarter. iheezo had another excellent quarter Unit demand was up 47% from last year and 3% sequentially. unit demand was up 47% from last year and 3% sequentially That's strong, sustained growth, and continued proof that IHEEZO's value proposition is resonating in the market. that's strong sustained growth and continued proof that iheezo's value proposition is resonating in the market As expected, the third quarter followed normal seasonality. as expected the third quarter followed normal seasonality A brief slowdown in July and August, but demand rebounded quickly in September and continued through October. a brief slowdown in july and august but demand rebounded quickly in september and continued through october With a large order already placed in October, entering its strongest quarter of the year when we typically see increased stocking activity, IHEEZO is well positioned for a strong finish to 2025 and real momentum heading into 2026. Our strategy is working exactly as planned. The retina pivot we executed last year, along with our new IHEEZO for All education initiative, is driving awareness, engagement, and adoption across retina practices. Nearly half of the accounts ordering IHEEZO this year are brand new, a clear sign that we're expanding reach and deepening loyalty. With an 86% reorder rate, IHEEZO is not only winning new users but also keeping them, a strong foundation for sustained growth ahead. Looking ahead, we're still just scratching the surface of IHEEZO's potential. We're in the very early stages of this growth story, and the opportunity ahead is tremendous. With a large order already placed in October, entering its strongest quarter of the year when we typically see increased stocking activity, IHEEZO is well positioned for a strong finish to 2025 and real momentum heading into 2026. with a large order already placed in october entering its strongest quarter of the year when we typically see increased stocking activity iheezo is well positioned for a strong finish to 2025 and real momentum heading into 2026 Our strategy is working exactly as planned. our strategy is working exactly as planned The retina pivot we executed last year, along with our new IHEEZO for All education initiative, is driving awareness, engagement, and adoption across retina practices. the retina pivot we executed last year along with our new iheezo for all education initiative is driving awareness engagement and adoption across retina practices Nearly half of the accounts ordering IHEEZO this year are brand new, a clear sign that we're expanding reach and deepening loyalty. nearly half of the accounts ordering iheezo this year are brand new a clear sign that we're expanding reach and deepening loyalty With an 86% reorder rate, IHEEZO is not only winning new users but also keeping them, a strong foundation for sustained growth ahead. with an 86% reorder rate iheezo is not only winning new users but also keeping them a strong foundation for sustained growth ahead Looking ahead, we're still just scratching the surface of IHEEZO's potential. looking ahead we're still just scratching the surface of iheezo's potential We're in the very early stages of this growth story, and the opportunity ahead is tremendous. we're in the very early stages of this growth story and the opportunity ahead is tremendous Our retina team is focused on both driving both breadth and depth, reaching new accounts and deepening relationships with existing customers, and expanding awareness among retina specialists. As adoption continues to grow, we're confident that IHEEZO will become an even stronger growth engine for Harrow, especially once we introduce our biosimilars starting in mid-2026. Shifting to TRIESENCE. TRIESENCE is showing real progress in the retina market. The trends we're seeing now indicate an acceleration in adoption and growing traction across the retinal community. Since relaunching TRIESENCE last October in 2024, there has been a four-times growth factor with significant headroom remaining. TRIESENCE unit demand grew 67% sequentially. Importantly, more than half of the accounts ordering TRIESENCE in the third quarter, about 53%, were new customers. That tells us our reach is expanding and physicians are responding to TRIESENCE's strong clinical performance and favorable reimbursement profile. Our retina team is focused on both driving both breadth and depth, reaching new accounts and deepening relationships with existing customers, and expanding awareness among retina specialists. our retina team is focused on both driving both breadth and depth reaching new accounts and deepening relationships with existing customers and expanding awareness among retina specialists As adoption continues to grow, we're confident that IHEEZO will become an even stronger growth engine for Harrow, especially once we introduce our biosimilars starting in mid-2026. as adoption continues to grow we're confident that iheezo will become an even stronger growth engine for harrow especially once we introduce our biosimilars starting in mid-2026 Shifting to TRIESENCE. shifting to triesence TRIESENCE is showing real progress in the retina market. triesence is showing real progress in the retina market The trends we're seeing now indicate an acceleration in adoption and growing traction across the retinal community. the trends we're seeing now indicate an acceleration in adoption and growing traction across the retinal community Since relaunching TRIESENCE last October in 2024, there has been a four-times growth factor with significant headroom remaining. since relaunching triesence last october in 2024 there has been a four-times growth factor with significant headroom remaining TRIESENCE unit demand grew 67% sequentially. triesence unit demand grew 67% sequentially Importantly, more than half of the accounts ordering TRIESENCE in the third quarter, about 53%, were new customers. importantly more than half of the accounts ordering triesence in the third quarter about 53% were new customers That tells us our reach is expanding and physicians are responding to TRIESENCE's strong clinical performance and favorable reimbursement profile. that tells us our reach is expanding and physicians are responding to triesence's strong clinical performance and favorable reimbursement profile With its proven safety, excellent efficacy, and broad payer coverage, TRIESENCE is well positioned to continue gaining share in the retina market. The big news is our official launch of TRIESENCE into the ocular inflammation market, the largest and most promising opportunity for the brand to date. We're still early in the launch, but the response from the field has been encouraging. Physicians are giving strong positive feedback, and early utilization trends are moving in the right direction. The early traction reinforced exactly what we believed from the start: that TRIESENCE delivers real clinical value and fits seamlessly into physician workflows. We see this launch as a true catalyst, opening a major new growth channel for TRIESENCE. With proven safety, strong efficacy, and broad payer coverage, TRIESENCE is gaining traction in the retina market and has just entered its largest opportunity yet: ocular inflammation with positive early feedback. With its proven safety, excellent efficacy, and broad payer coverage, TRIESENCE is well positioned to continue gaining share in the retina market. with its proven safety excellent efficacy and broad payer coverage triesence is well positioned to continue gaining share in the retina market The big news is our official launch of TRIESENCE into the ocular inflammation market, the largest and most promising opportunity for the brand to date. the big news is our official launch of triesence into the ocular inflammation market the largest and most promising opportunity for the brand to date We're still early in the launch, but the response from the field has been encouraging. we're still early in the launch but the response from the field has been encouraging Physicians are giving strong positive feedback, and early utilization trends are moving in the right direction. physicians are giving strong positive feedback and early utilization trends are moving in the right direction The early traction reinforced exactly what we believed from the start: that TRIESENCE delivers real clinical value and fits seamlessly into physician workflows. the early traction reinforced exactly what we believed from the start that triesence delivers real clinical value and fits seamlessly into physician workflows We see this launch as a true catalyst, opening a major new growth channel for TRIESENCE. we see this launch as a true catalyst opening a major new growth channel for triesence With proven safety, strong efficacy, and broad payer coverage, TRIESENCE is gaining traction in the retina market and has just entered its largest opportunity yet: ocular inflammation with positive early feedback. with proven safety strong efficacy and broad payer coverage triesence is gaining traction in the retina market and has just entered its largest opportunity yet ocular inflammation with positive early feedback As awareness builds and adoption expands, I'm confident TRIESENCE will become a key growth driver and increasingly important contributor to Harrow's leadership in ophthalmic care. Turning to rare and specialty products, this is an area of untapped potential for Harrow. Earlier this quarter, we're excited to welcome Tom Pertallo as the Vice President of this segment. Tom brings deep commercial experience and a proven track record of driving growth, and his leadership comes at exactly the right time as we work to unlock the full value of this portfolio. Right now, these products represent less than 1% of the total market volume, which means the upside is significant. With Tom leading the charge and a dedicated sales force being built to focus exclusively on this business, we're tightening execution, re-energizing our commercial approach, and positioning these brands to return to growth. As awareness builds and adoption expands, I'm confident TRIESENCE will become a key growth driver and increasingly important contributor to Harrow's leadership in ophthalmic care. as awareness builds and adoption expands i'm confident triesence will become a key growth driver and increasingly important contributor to harrow's leadership in ophthalmic care Turning to rare and specialty products, this is an area of untapped potential for Harrow. turning to rare and specialty products this is an area of untapped potential for harrow Earlier this quarter, we're excited to welcome Tom Pertallo as the Vice President of this segment. earlier this quarter we're excited to welcome tom pertallo as the vice president of this segment Tom brings deep commercial experience and a proven track record of driving growth, and his leadership comes at exactly the right time as we work to unlock the full value of this portfolio. tom brings deep commercial experience and a proven track record of driving growth and his leadership comes at exactly the right time as we work to unlock the full value of this portfolio Right now, these products represent less than 1% of the total market volume, which means the upside is significant. right now these products represent less than 1% of the total market volume which means the upside is significant With Tom leading the charge and a dedicated sales force being built to focus exclusively on this business, we're tightening execution, re-energizing our commercial approach, and positioning these brands to return to growth. with tom leading the charge and a dedicated sales force being built to focus exclusively on this business we're tightening execution re-energizing our commercial approach and positioning these brands to return to growth We're also launching the Harrow Access for All program this quarter, which will improve affordability and expand patient access. Key levers to drive sustainable growth across the portfolio. This portfolio once generated nearly $10 million quarterly revenue, and we see a clear path to reignite that growth and ultimately exceed those levels. With strong leadership now in place, renewed focus, and clear strategies in place, I'm confident this business is positioned to return for growth and deliver stronger, more consistent performance moving forward. To close, I couldn't be more excited about where Harrow is headed. We're still very early in the growth stages across all of our key growth drivers, with significant catalysts and ample room for further growth. We are well positioned for our next stage of growth. Our commercial momentum is strong, the plan is clear, and the opportunities in front of us are huge. We're also launching the Harrow Access for All program this quarter, which will improve affordability and expand patient access. we're also launching the harrow access for all program this quarter which will improve affordability and expand patient access Key levers to drive sustainable growth across the portfolio. key levers to drive sustainable growth across the portfolio This portfolio once generated nearly $10 million quarterly revenue, and we see a clear path to reignite that growth and ultimately exceed those levels. this portfolio once generated nearly $10 million quarterly revenue and we see a clear path to reignite that growth and ultimately exceed those levels With strong leadership now in place, renewed focus, and clear strategies in place, I'm confident this business is positioned to return for growth and deliver stronger, more consistent performance moving forward. with strong leadership now in place renewed focus and clear strategies in place i'm confident this business is positioned to return for growth and deliver stronger more consistent performance moving forward To close, I couldn't be more excited about where Harrow is headed. to close i couldn't be more excited about where harrow is headed We're still very early in the growth stages across all of our key growth drivers, with significant catalysts and ample room for further growth. we're still very early in the growth stages across all of our key growth drivers with significant catalysts and ample room for further growth We are well positioned for our next stage of growth. we are well positioned for our next stage of growth Our commercial momentum is strong, the plan is clear, and the opportunities in front of us are huge. our commercial momentum is strong the plan is clear and the opportunities in front of us are huge In dry eye, VEVYE continues to lead the charge, expanding its share, broadening access, improving coverage, and deepening adoption among prescribers. In retina, we're strengthening relationships, expanding awareness, and gearing up for two major launches: BioViz in mid-2026 and OpioViz in mid-2027. In the surgical segment, we're building a differentiated portfolio that supports the perioperative space, delivering efficiency and value for practices. In rare and specialty, new leadership, a focused plan of action, and the launch of Harrow Access for All are unlocking the potential of a diverse portfolio that represents less than 1% of its addressable market today. The opportunity across these four segments is tremendous. With best-in-class products, a scalable commercial platform, and a disciplined strategy for execution, we're building a company with durable, long-term growth potential. Harrow's path forward is clear: stronger execution, expanding leadership, and sustained momentum across every part of the business. In dry eye, VEVYE continues to lead the charge, expanding its share, broadening access, improving coverage, and deepening adoption among prescribers. in dry eye vevye continues to lead the charge expanding its share broadening access improving coverage and deepening adoption among prescribers In retina, we're strengthening relationships, expanding awareness, and gearing up for two major launches: BioViz in mid-2026 and OpioViz in mid-2027. in retina we're strengthening relationships expanding awareness and gearing up for two major launches bioviz in mid-2026 and opioviz in mid-2027 In the surgical segment, we're building a differentiated portfolio that supports the perioperative space, delivering efficiency and value for practices. in the surgical segment we're building a differentiated portfolio that supports the perioperative space delivering efficiency and value for practices In rare and specialty, new leadership, a focused plan of action, and the launch of Harrow Access for All are unlocking the potential of a diverse portfolio that represents less than 1% of its addressable market today. in rare and specialty new leadership a focused plan of action and the launch of harrow access for all are unlocking the potential of a diverse portfolio that represents less than 1% of its addressable market today The opportunity across these four segments is tremendous. the opportunity across these four segments is tremendous With best-in-class products, a scalable commercial platform, and a disciplined strategy for execution, we're building a company with durable, long-term growth potential. with best-in-class products a scalable commercial platform and a disciplined strategy for execution we're building a company with durable long-term growth potential Harrow's path forward is clear: stronger execution, expanding leadership, and sustained momentum across every part of the business. harrow's path forward is clear stronger execution expanding leadership and sustained momentum across every part of the business With that, we can turn it over to the operator for Q&A. With that, we can turn it over to the operator for Q&A. with that we can turn it over to the operator for q&a

Speaker 10: If your question has been answered and you'd like to remove yourself from the queue, press star one again. Our first question comes from Jeffrey Cohen with Ladenburg. Your line is open. If your question has been answered and you'd like to remove yourself from the queue, press star one again. if your question has been answered and you'd like to remove yourself from the queue press star one again Our first question comes from Jeffrey Cohen with Ladenburg. our first question comes from jeffrey cohen with ladenburg Your line is open. your line is open

Speaker 6: Hey, good morning. Thanks for taking our questions and congrats on the quarter. A couple from Aaron. Firstly, could you talk about VEVYE prescription data and why we do not see it this quarter? Hey, good morning. hey good morning Thanks for taking our questions and congrats on the quarter. thanks for taking our questions and congrats on the quarter A couple from Aaron. a couple from aaron Firstly, could you talk about VEVYE prescription data and why we do not see it this quarter? firstly could you talk about vevye prescription data and why we do not see it this quarter

Speaker 13: Hey, Jeff, this is Mark. Thanks for the question. What we decided to do is to make sure that we have the most accurate information available. As you know, we withdrew from some of the reporting services, some of the data reporting services, a few quarters ago. It is really important that we have confidence, absolute confidence, that what we are putting out is as accurate as possible. Hey, Jeff, this is Mark. hey jeff this is mark Thanks for the question. thanks for the question What we decided to do is to make sure that we have the most accurate information available. what we decided to do is to make sure that we have the most accurate information available As you know, we withdrew from some of the reporting services, some of the data reporting services, a few quarters ago. as you know we withdrew from some of the reporting services some of the data reporting services a few quarters ago It is really important that we have confidence, absolute confidence, that what we are putting out is as accurate as possible. it is really important that we have confidence absolute confidence that what we are putting out is as accurate as possible From our perspective, I think the key metric was revenue generated from these products and not necessarily IQ via data or data from a data feed that may or may not be completely accurate. Because of that, we decided to change the way that we're reporting. Andrew, do you want to add to that at all? From our perspective, I think the key metric was revenue generated from these products and not necessarily IQ via data or data from a data feed that may or may not be completely accurate. from our perspective i think the key metric was revenue generated from these products and not necessarily iq via data or data from a data feed that may or may not be completely accurate Because of that, we decided to change the way that we're reporting. because of that we decided to change the way that we're reporting Andrew, do you want to add to that at all? andrew do you want to add to that at all

Speaker 3: Yeah, and thanks, Jeff. The only other part of that to add to what Mark was saying is really one of the reasons we kind of were pulling out of these third-party aggregators were for competitive reasons. If we're doing that, it didn't really make sense to us to present the data, to then present the data and make it available to all of our competitors in our earnings release. That's driven a lot of the decision-making with presentation of the TRX data. Yeah, and thanks, Jeff. yeah and thanks jeff The only other part of that to add to what Mark was saying is really one of the reasons we kind of were pulling out of these third-party aggregators were for competitive reasons. the only other part of that to add to what mark was saying is really one of the reasons we kind of were pulling out of these third-party aggregators were for competitive reasons If we're doing that, it didn't really make sense to us to present the data, to then present the data and make it available to all of our competitors in our earnings release. if we're doing that it didn't really make sense to us to present the data to then present the data and make it available to all of our competitors in our earnings release That's driven a lot of the decision-making with presentation of the TRX data. that's driven a lot of the decision-making with presentation of the trx data To Mark's point, we're going to do our best to be transparent about the progress of VEVYE without giving up competitive positioning. To Mark's point, we're going to do our best to be transparent about the progress of VEVYE without giving up competitive positioning. to mark's point we're going to do our best to be transparent about the progress of vevye without giving up competitive positioning

Speaker 6: Okay, that's perfect. Secondly, maybe for you, Andrew, could you talk about the leverage that you're achieving? You had some pretty nice leverage on the SG&A in the third quarter, but as you continue to expand your commercial teams, how should we think about leverage overall into 2026, mainly as a percent of revenues? Okay, that's perfect. okay that's perfect Secondly, maybe for you, Andrew, could you talk about the leverage that you're achieving? secondly maybe for you andrew could you talk about the leverage that you're achieving You had some pretty nice leverage on the SG&A in the third quarter, but as you continue to expand your commercial teams, how should we think about leverage overall into 2026, mainly as a percent of revenues? you had some pretty nice leverage on the sg&a in the third quarter but as you continue to expand your commercial teams how should we think about leverage overall into 2026 mainly as a percent of revenues

Speaker 3: Yeah, and this has been a topic for us that we've brought up for a long time now, where we expected to see operating leverage, especially this year in the model on the new revenue growth we expected. We spent a lot of money on the operational and commercial infrastructure to support the branded group. That is mostly in place, and we're seeing that leverage show up in the numbers. Yeah, and this has been a topic for us that we've brought up for a long time now, where we expected to see operating leverage, especially this year in the model on the new revenue growth we expected. yeah and this has been a topic for us that we've brought up for a long time now where we expected to see operating leverage especially this year in the model on the new revenue growth we expected We spent a lot of money on the operational and commercial infrastructure to support the branded group. we spent a lot of money on the operational and commercial infrastructure to support the branded group That is mostly in place, and we're seeing that leverage show up in the numbers. that is mostly in place and we're seeing that leverage show up in the numbers Obviously, Q3, we had great Chad Brines just under $23 million. The business is producing a lot of cash, about $16 million of cash in the third quarter from operations. As we look out, Pat talked a little bit about adding to that commercial infrastructure to drive revenue. The additional OpEx that we're looking at is revenue-generating OpEx. We should start seeing immediate return on that expense. Again, even though we're going to be making investments in the commercial infrastructure, it's not like it's going to be a 50% increase in OpEx. It's going to be a moderate increase. Importantly, and this is probably the most important thing, that investment in the expense should see almost an immediate impact and return on revenue. Obviously, Q3, we had great Chad Brines just under $23 million. obviously q3 we had great chad brines just under $23 million The business is producing a lot of cash, about $16 million of cash in the third quarter from operations. the business is producing a lot of cash about $16 million of cash in the third quarter from operations As we look out, Pat talked a little bit about adding to that commercial infrastructure to drive revenue. as we look out pat talked a little bit about adding to that commercial infrastructure to drive revenue The additional OpEx that we're looking at is revenue-generating OpEx. the additional opex that we're looking at is revenue-generating opex We should start seeing immediate return on that expense. we should start seeing immediate return on that expense Again, even though we're going to be making investments in the commercial infrastructure, it's not like it's going to be a 50% increase in OpEx. again even though we're going to be making investments in the commercial infrastructure it's not like it's going to be a 50% increase in opex It's going to be a moderate increase. it's going to be a moderate increase Importantly, and this is probably the most important thing, that investment in the expense should see almost an immediate impact and return on revenue. importantly and this is probably the most important thing that investment in the expense should see almost an immediate impact and return on revenue

Speaker 6: Okay, got it. Thanks for taking our questions. Congrats on the quarter. Okay, got it. okay got it Thanks for taking our questions. thanks for taking our questions Congrats on the quarter. congrats on the quarter

Speaker 13: Thank you, Jeff. Thank you, Jeff. thank you jeff

Speaker 3: Thanks, Jeff. Thanks, Jeff. thanks jeff

Speaker 10: Thank you. Thank you. thank you Our next question comes from Chase Knickerbocker with Craig Hallum. Your line is open. Our next question comes from Chase Knickerbocker with Craig Hallum. our next question comes from chase knickerbocker with craig hallum Your line is open. your line is open

Speaker 1: Good morning. Thanks for taking the questions. Maybe just first to start, a couple on VEVYE. Mark, you had mentioned in the stockholder letter that ASP was down modestly sequentially in Q3. Could you just define the magnitude of that modest decline for us just so we can kind of understand that? And then just as we think about, you kind of spoke to stabilization in the near term. Can you just walk us through some of your modeling assumptions on VEVYE that kind of lead to that ASP stabilization in the near term? Is it improving mix that you're seeing so far in October? And then I've got a follow-up. Thanks. Good morning. good morning Thanks for taking the questions. thanks for taking the questions Maybe just first to start, a couple on VEVYE. maybe just first to start a couple on vevye Mark, you had mentioned in the stockholder letter that ASP was down modestly sequentially in Q3. mark you had mentioned in the stockholder letter that asp was down modestly sequentially in q3 Could you just define the magnitude of that modest decline for us just so we can kind of understand that? could you just define the magnitude of that modest decline for us just so we can kind of understand that And then just as we think about, you kind of spoke to stabilization in the near term. and then just as we think about you kind of spoke to stabilization in the near term Can you just walk us through some of your modeling assumptions on VEVYE that kind of lead to that ASP stabilization in the near term? can you just walk us through some of your modeling assumptions on vevye that kind of lead to that asp stabilization in the near term Is it improving mix that you're seeing so far in October? is it improving mix that you're seeing so far in october And then I've got a follow-up. and then i've got a follow-up Thanks. thanks

Speaker 13: Thanks for the question, Chase. In terms of defining what modestly means, I can't give you a definition with precision. Thanks for the question, Chase. thanks for the question chase In terms of defining what modestly means, I can't give you a definition with precision. in terms of defining what modestly means i can't give you a definition with precision I mean, I think it's less than 10%. I think the more important issue is how is ASP or net revenue per unit, how is that going to stabilize in the near term? Then, as I said on prior calls, begin to float up. What is the justification for that? To be very clear, we're really counting on coverage coming through. We're counting on the ratio of covered prescriptions versus cash-pay prescriptions to flip or begin to change so that there's more of a bias towards covered prescriptions versus cash-pay prescriptions. If that happens, that's when you see the stabilization happen. That's when you see the ASP begin to float up. I mean, I think it's less than 10%. i mean i think it's less than 10% I think the more important issue is how is ASP or net revenue per unit, how is that going to stabilize in the near term? i think the more important issue is how is asp or net revenue per unit how is that going to stabilize in the near term Then, as I said on prior calls, begin to float up. then as i said on prior calls begin to float up What is the justification for that? what is the justification for that To be very clear, we're really counting on coverage coming through. to be very clear we're really counting on coverage coming through We're counting on the ratio of covered prescriptions versus cash-pay prescriptions to flip or begin to change so that there's more of a bias towards covered prescriptions versus cash-pay prescriptions. we're counting on the ratio of covered prescriptions versus cash-pay prescriptions to flip or begin to change so that there's more of a bias towards covered prescriptions versus cash-pay prescriptions If that happens, that's when you see the stabilization happen. if that happens that's when you see the stabilization happen That's when you see the ASP begin to float up. that's when you see the asp begin to float up The beautiful thing, I think, the exciting thing for us, and I think you've actually noted this in your notes that I've seen, is that that increase will affect the entire corpus, every single unit of VEVYE. The question is how and when is that going to happen? I tried to address that in the letter to stockholders. We discussed that in our prepared remarks. We now have landed this coverage win with the largest Pharmacy Benefit Manager in the U.S., and specifically their commercial lives group. You're talking about tens of millions of new potential lives covered. When you think about that ratio of covered prescriptions versus cash-pay prescriptions, beginning January 1, we anticipate that ratio is going to begin to flip. The beautiful thing, I think, the exciting thing for us, and I think you've actually noted this in your notes that I've seen, is that that increase will affect the entire corpus, every single unit of VEVYE. the beautiful thing i think the exciting thing for us and i think you've actually noted this in your notes that i've seen is that that increase will affect the entire corpus every single unit of vevye The question is how and when is that going to happen? the question is how and when is that going to happen I tried to address that in the letter to stockholders. i tried to address that in the letter to stockholders We discussed that in our prepared remarks. we discussed that in our prepared remarks We now have landed this coverage win with the largest Pharmacy Benefit Manager in the U.S., and specifically their commercial lives group. we now have landed this coverage win with the largest pharmacy benefit manager in the u.s and specifically their commercial lives group You're talking about tens of millions of new potential lives covered. you're talking about tens of millions of new potential lives covered When you think about that ratio of covered prescriptions versus cash-pay prescriptions, beginning January 1, we anticipate that ratio is going to begin to flip. when you think about that ratio of covered prescriptions versus cash-pay prescriptions beginning january 1 we anticipate that ratio is going to begin to flip Actually, to be candid with you, I've had doctors send me letters that I know that have already gone out from this benefit manager to the physicians, letting them know about the plan changes that will take effect, drugs that will not be covered, and the specific patients' names who will no longer be covered for that product, and letting them know what the new formulary looks like. This is really exciting for VEVYE. We expect to start seeing some of those changes, those prescription flips from other dry eye products to VEVYE in the fourth quarter. We expect that'll start to happen, but it'll really kick in in the first quarter. As I said, once that takes place, that ratio of covered versus cash-pay will begin to change. You'll see that stabilization happen. Actually, to be candid with you, I've had doctors send me letters that I know that have already gone out from this benefit manager to the physicians, letting them know about the plan changes that will take effect, drugs that will not be covered, and the specific patients' names who will no longer be covered for that product, and letting them know what the new formulary looks like. actually to be candid with you i've had doctors send me letters that i know that have already gone out from this benefit manager to the physicians letting them know about the plan changes that will take effect drugs that will not be covered and the specific patients' names who will no longer be covered for that product and letting them know what the new formulary looks like This is really exciting for VEVYE. this is really exciting for vevye We expect to start seeing some of those changes, those prescription flips from other dry eye products to VEVYE in the fourth quarter. we expect to start seeing some of those changes those prescription flips from other dry eye products to vevye in the fourth quarter We expect that'll start to happen, but it'll really kick in in the first quarter. we expect that'll start to happen but it'll really kick in in the first quarter As I said, once that takes place, that ratio of covered versus cash-pay will begin to change. as i said once that takes place that ratio of covered versus cash-pay will begin to change You'll see that stabilization happen. you'll see that stabilization happen I think, as I said in the last call, we'll start to see, I think, a bias towards ASP improving and potentially improving maybe even more than modestly. I think, as I said in the last call, we'll start to see, I think, a bias towards ASP improving and potentially improving maybe even more than modestly. i think as i said in the last call we'll start to see i think a bias towards asp improving and potentially improving maybe even more than modestly

Speaker 1: Yeah, that's what I was hoping to follow up on, is just any more specifics you'd be willing to share as far as that, the largest PBM, that win? Was it their commercial plans? Was it commercial and Medicare? Just any sort of details there. As we think about that ASP improvement, to your point, any way you can help us kind of define how you see your current volume and kind of the amount of your current volume that could benefit from that win and how that affects ASP and any thoughts you'd be willing to give there as we enter next year? Yeah, that's what I was hoping to follow up on, is just any more specifics you'd be willing to share as far as that, the largest PBM, that win? yeah that's what i was hoping to follow up on is just any more specifics you'd be willing to share as far as that the largest pbm that win Was it their commercial plans? was it their commercial plans Was it commercial and Medicare? was it commercial and medicare Just any sort of details there. just any sort of details there As we think about that ASP improvement, to your point, any way you can help us kind of define how you see your current volume and kind of the amount of your current volume that could benefit from that win and how that affects ASP and any thoughts you'd be willing to give there as we enter next year? as we think about that asp improvement to your point any way you can help us kind of define how you see your current volume and kind of the amount of your current volume that could benefit from that win and how that affects asp and any thoughts you'd be willing to give there as we enter next year

Speaker 13: Yeah, I would say that these are commercial lives, number one. Yeah, I would say that these are commercial lives, number one. yeah i would say that these are commercial lives number one They're, I would say, the most attractive of those lives that you can get. It's a major coverage win. I was talking to our team earlier, and I said, "I hope that our investors, the main takeaway from the stockholder letter, I think it's the most important part of the stockholder letter, is this coverage win because it dramatically changes things." I mean, if you get a $20 or $30 or $40 improvement, and I'm not suggesting that we'll see a $40 improvement on ASP, but if it's a $20 improvement, as an example, it affects every single one of those units. As units are growing, and they will grow regardless, we are going to see significant improvement in total units for VEVYE. The question is, how much money are we going to make from all of those units? They're, I would say, the most attractive of those lives that you can get. they're i would say the most attractive of those lives that you can get It's a major coverage win. it's a major coverage win I was talking to our team earlier, and I said, "I hope that our investors, the main takeaway from the stockholder letter, I think it's the most important part of the stockholder letter, is this coverage win because it dramatically changes things." I mean, if you get a $20 or $30 or $40 improvement, and I'm not suggesting that we'll see a $40 improvement on ASP, but if it's a $20 improvement, as an example, it affects every single one of those units. i was talking to our team earlier and i said "i hope that our investors the main takeaway from the stockholder letter i think it's the most important part of the stockholder letter is this coverage win because it dramatically changes things." i mean if you get a $20 or $30 or $40 improvement and i'm not suggesting that we'll see a $40 improvement on asp but if it's a $20 improvement as an example it affects every single one of those units As units are growing, and they will grow regardless, we are going to see significant improvement in total units for VEVYE. as units are growing and they will grow regardless we are going to see significant improvement in total units for vevye The question is, how much money are we going to make from all of those units? the question is how much money are we going to make from all of those units I think that this improvement in coverage is going to be a major factor at the beginning of this coming year. You also know that we are very conservative in terms of how we invest commercially. We do not do extravaganza launches because we dip our toes into the water. We kind of get in. We see what works. It is just our style, and it is the way that we have been able to invest in new product launches. For us to now make investments in VEVYE and specifically open up 10 new territories in the very near term, I think by the middle part of next year, we are going to have upwards of about 100 total territories for VEVYE. I think that this improvement in coverage is going to be a major factor at the beginning of this coming year. i think that this improvement in coverage is going to be a major factor at the beginning of this coming year You also know that we are very conservative in terms of how we invest commercially. you also know that we are very conservative in terms of how we invest commercially We do not do extravaganza launches because we dip our toes into the water. we do not do extravaganza launches because we dip our toes into the water We kind of get in. we kind of get in We see what works. It is just our style, and it is the way that we have been able to invest in new product launches. we see what works. it is just our style and it is the way that we have been able to invest in new product launches For us to now make investments in VEVYE and specifically open up 10 new territories in the very near term, I think by the middle part of next year, we are going to have upwards of about 100 total territories for VEVYE. for us to now make investments in vevye and specifically open up 10 new territories in the very near term i think by the middle part of next year, we are going to have upwards of about 100 total territories for vevye The reason why we're making those investments is because, candidly, it would be malpractice for us not to make those investments now that we have such strong coverage in these specific markets. We're very bullish on VEVYE next year. I think you can expect to see some improvements in ASP as this ratio begins to flip and bias more covered versus cash-pay prescriptions. It's a really good time for VEVYE. The drug, by the way, is phenomenal. If you've ever put the drug in your eye, it's phenomenal. I think it's the best product in the class. It does a great job, and patients love it. The refill rates are absolutely extraordinary. I believe best in class. The reason why we're making those investments is because, candidly, it would be malpractice for us not to make those investments now that we have such strong coverage in these specific markets. the reason why we're making those investments is because candidly it would be malpractice for us not to make those investments now that we have such strong coverage in these specific markets We're very bullish on VEVYE next year. we're very bullish on vevye next year I think you can expect to see some improvements in ASP as this ratio begins to flip and bias more covered versus cash-pay prescriptions. i think you can expect to see some improvements in asp as this ratio begins to flip and bias more covered versus cash-pay prescriptions It's a really good time for VEVYE. it's a really good time for vevye The drug, by the way, is phenomenal. the drug by the way is phenomenal If you've ever put the drug in your eye, it's phenomenal. if you've ever put the drug in your eye it's phenomenal I think it's the best product in the class. i think it's the best product in the class It does a great job, and patients love it. it does a great job and patients love it The refill rates are absolutely extraordinary. the refill rates are absolutely extraordinary I believe best in class. i believe best in class

Speaker 1: Very helpful caller, Mark. Thank you. Very helpful caller, Mark. very helpful caller mark Thank you. thank you

Speaker 13: Thanks, Chase. Thanks, Chase. thanks chase

Speaker 10: Thank you. Our next question comes from Steve Seedhouse with Cantor. Your line is open. Hey, good morning. Thank you. thank you Our next question comes from Steve Seedhouse with Cantor. our next question comes from steve seedhouse with cantor Your line is open. your line is open Hey, good morning. hey good morning

Speaker 4: Thanks for the question. Hoping just to start, you could give us a sense of what proportion of the VEVYE cash-pay patients currently you'd actually expect to transition to insurance coverage in 2026 and just ballpark the expected impact that that particular variable would have on net price per unit. Thanks for the question. thanks for the question Hoping just to start, you could give us a sense of what proportion of the VEVYE cash-pay patients currently you'd actually expect to transition to insurance coverage in 2026 and just ballpark the expected impact that that particular variable would have on net price per unit. hoping just to start you could give us a sense of what proportion of the vevye cash-pay patients currently you'd actually expect to transition to insurance coverage in 2026 and just ballpark the expected impact that that particular variable would have on net price per unit

Speaker 13: Yeah, thanks for the question, Steve. I don't know that we can give you the answer with precision. We actually have built internal models to try and estimate what that would look like. This is the largest commercial PBM. If you just model out how many dry eye patients they have, and we do know how many dry eye prescriptions come from those plans, we can see a couple of things happening. Yeah, thanks for the question, Steve. yeah thanks for the question steve I don't know that we can give you the answer with precision. i don't know that we can give you the answer with precision We actually have built internal models to try and estimate what that would look like. we actually have built internal models to try and estimate what that would look like This is the largest commercial PBM. this is the largest commercial pbm If you just model out how many dry eye patients they have, and we do know how many dry eye prescriptions come from those plans, we can see a couple of things happening. if you just model out how many dry eye patients they have and we do know how many dry eye prescriptions come from those plans we can see a couple of things happening One, as I said, there are patients that have been denied coverage from those plans who are paying cash, who we will be able to reach out to and hopefully transition them from cash-pay to cover because this is not just a non-preferred brand status. This is a preferred status, or this is the lowest, or in some cases, no copay type coverage. It is really favorable coverage for VEVYE. Of course, we, as I said, are seeing the letters that have already gone out to physicians, letting them know that legacy products that patients were being prescribed are no longer covered. I know what those specific products are. I was looking at the number of patients, of course, not looking at the specific patients' names or any of that, but just one physician in one small community on one street, the number of patients. One, as I said, there are patients that have been denied coverage from those plans who are paying cash, who we will be able to reach out to and hopefully transition them from cash-pay to cover because this is not just a non-preferred brand status. one as i said there are patients that have been denied coverage from those plans who are paying cash who we will be able to reach out to and hopefully transition them from cash-pay to cover because this is not just a non-preferred brand status This is a preferred status, or this is the lowest, or in some cases, no copay type coverage. this is a preferred status or this is the lowest or in some cases no copay type coverage It is really favorable coverage for VEVYE. it is really favorable coverage for vevye Of course, we, as I said, are seeing the letters that have already gone out to physicians, letting them know that legacy products that patients were being prescribed are no longer covered. of course we as i said, are seeing the letters that have already gone out to physicians letting them know that legacy products that patients were being prescribed are no longer covered I know what those specific products are. i know what those specific products are I was looking at the number of patients, of course, not looking at the specific patients' names or any of that, but just one physician in one small community on one street, the number of patients. i was looking at the number of patients of course not looking at the specific patients' names or any of that but just one physician in one small community on one street the number of patients You start adding up these letters going out to thousands and thousands of physicians, and it could absolutely hit what we are thinking about internally in our modeling. Andrew, do you want to add to that at all? You start adding up these letters going out to thousands and thousands of physicians, and it could absolutely hit what we are thinking about internally in our modeling. you start adding up these letters going out to thousands and thousands of physicians and it could absolutely hit what we are thinking about internally in our modeling Andrew, do you want to add to that at all? andrew do you want to add to that at all

Speaker 3: Yeah, I think the one thing that I'm really excited about this coverage win is it kind of shows what the—and I think we're going to really see it next year as we demonstrate the power of VAPA, which is really a long—the VAPA program is almost called a temporary program. It's not meant to be the program forever. The goal of the program is to gain coverage wins and increase patient access through insurance reimbursement. Through that, we think ASP will improve. Yeah, I think the one thing that I'm really excited about this coverage win is it kind of shows what the—and I think we're going to really see it next year as we demonstrate the power of VAPA, which is really a long—the VAPA program is almost called a temporary program. yeah i think the one thing that i'm really excited about this coverage win is it kind of shows what the—and i think we're going to really see it next year as we demonstrate the power of vapa which is really a long—the vapa program is almost called a temporary program It's not meant to be the program forever. it's not meant to be the program forever The goal of the program is to gain coverage wins and increase patient access through insurance reimbursement. the goal of the program is to gain coverage wins and increase patient access through insurance reimbursement Through that, we think ASP will improve. through that we think asp will improve What's great about the program, though, is it also sets us up where we kind of have a base to work off of when we're negotiating with PBMs and payers. There's no reason for us to take less money from a payer. When we're bidding, we're not going to bid ourselves into a hole. The VAPA program is working really well. I mean, it's exceeding our expectations on the cash-pay side. What that's doing is setting us up for a lot of long-term growth for the product, especially as the insurance wins come in. We think they will. We think that the program itself, just with the volume and demand we're seeing, brings us more negotiating power when we go to the payers and go through these bid cycles. I think, like I said, the first coverage win is a good demonstration of that. What's great about the program, though, is it also sets us up where we kind of have a base to work off of when we're negotiating with PBMs and payers. what's great about the program though is it also sets us up where we kind of have a base to work off of when we're negotiating with pbms and payers There's no reason for us to take less money from a payer. there's no reason for us to take less money from a payer When we're bidding, we're not going to bid ourselves into a hole. when we're bidding we're not going to bid ourselves into a hole The VAPA program is working really well. the vapa program is working really well I mean, it's exceeding our expectations on the cash-pay side. i mean it's exceeding our expectations on the cash-pay side What that's doing is setting us up for a lot of long-term growth for the product, especially as the insurance wins come in. what that's doing is setting us up for a lot of long-term growth for the product especially as the insurance wins come in We think they will. we think they will We think that the program itself, just with the volume and demand we're seeing, brings us more negotiating power when we go to the payers and go through these bid cycles. we think that the program itself just with the volume and demand we're seeing brings us more negotiating power when we go to the payers and go through these bid cycles I think, like I said, the first coverage win is a good demonstration of that. i think like i said the first coverage win is a good demonstration of that We should see more of that in 2026 and 2027. We should see more of that in 2026 and 2027. we should see more of that in 2026 and 2027

Speaker 4: I just want to ask, focusing on, I guess, fourth quarter specifically. On that point, you were just noting you're in this moment, right, where the volume growth is tremendous, and you have this sort of couple-month window between now and 2026 where it would be critical to keep people on drug until their insurance coverage kicks in. Are you doing anything like providing free prescriptions beyond the first month to VAPA patients or just anything new to bridge that gap given the new coverage decisions that would impact fourth-quarter revenue? On the flip side, just with the addition of the new specialty pharmacies, is there any expected inventory or stocking or sort of one-time impact to fourth quarter that we should be considering for our models? I just want to ask, focusing on, I guess, fourth quarter specifically. i just want to ask focusing on i guess fourth quarter specifically On that point, you were just noting you're in this moment, right, where the volume growth is tremendous, and you have this sort of couple-month window between now and 2026 where it would be critical to keep people on drug until their insurance coverage kicks in. on that point you were just noting you're in this moment right where the volume growth is tremendous and you have this sort of couple-month window between now and 2026 where it would be critical to keep people on drug until their insurance coverage kicks in Are you doing anything like providing free prescriptions beyond the first month to VAPA patients or just anything new to bridge that gap given the new coverage decisions that would impact fourth-quarter revenue? are you doing anything like providing free prescriptions beyond the first month to vapa patients or just anything new to bridge that gap given the new coverage decisions that would impact fourth-quarter revenue On the flip side, just with the addition of the new specialty pharmacies, is there any expected inventory or stocking or sort of one-time impact to fourth quarter that we should be considering for our models? on the flip side just with the addition of the new specialty pharmacies is there any expected inventory or stocking or sort of one-time impact to fourth quarter that we should be considering for our models

Speaker 13: Andrew, why don't you take the last question, and I'll touch on the first question and ask Pat for some guidance as well. Andrew, why don't you take the last question, and I'll touch on the first question and ask Pat for some guidance as well. andrew why don't you take the last question and i'll touch on the first question and ask pat for some guidance as well

Speaker 3: Yeah, on any inventory stocking, Steve, I don't think we'll see anything really that impactful with VEVYE in particular for the fourth quarter. These guys are ordering pretty almost just-in-time type ordering, not quite that regularly, but I would say they're taking less inventory than wholesalers typically would. No real end-of-year impact related to that. Yeah, on any inventory stocking, Steve, I don't think we'll see anything really that impactful with VEVYE in particular for the fourth quarter. yeah on any inventory stocking steve i don't think we'll see anything really that impactful with vevye in particular for the fourth quarter These guys are ordering pretty almost just-in-time type ordering, not quite that regularly, but I would say they're taking less inventory than wholesalers typically would. these guys are ordering pretty almost just-in-time type ordering not quite that regularly but i would say they're taking less inventory than wholesalers typically would No real end-of-year impact related to that. no real end-of-year impact related to that

Speaker 4: Specifically on keeping patients on therapy, I don't know that we want to go into any specific tactics, but I know that the dry eye team, Maria and her entire team are hustling. Pat, you want to add to that at all? Specifically on keeping patients on therapy, I don't know that we want to go into any specific tactics, but I know that the dry eye team, Maria and her entire team are hustling. specifically on keeping patients on therapy i don't know that we want to go into any specific tactics but i know that the dry eye team maria and her entire team are hustling Pat, you want to add to that at all? pat you want to add to that at all

Speaker 12: Yeah, thanks, Mark. I think this is a super exciting opportunity, and this is part of the plan. Yeah, thanks, Mark. yeah thanks mark I think this is a super exciting opportunity, and this is part of the plan. i think this is a super exciting opportunity and this is part of the plan I think, to me, we have a very, very clear activation plan to really take advantage of evolving from FAPA to support these patients to really capitalize on our managed care wins. I think, to me, it is very much focused on the communications that are happening from the plans at this point in time to their patients, making sure that doctors know about our VAPA program and these wins that are going to be taking place to ultimately support the patient at the end of the year. We have a very robust high-touch program that is taking place and activating as we speak now that will continue to wrap up the year to support these patients and really accelerate growth at the end of the year. I think, in addition, our program right now, our fill program in VAPA, is a very high-touch program. I think, to me, we have a very, very clear activation plan to really take advantage of evolving from FAPA to support these patients to really capitalize on our managed care wins. i think to me we have a very very clear activation plan to really take advantage of evolving from fapa to support these patients to really capitalize on our managed care wins I think, to me, it is very much focused on the communications that are happening from the plans at this point in time to their patients, making sure that doctors know about our VAPA program and these wins that are going to be taking place to ultimately support the patient at the end of the year. i think to me, it is very much focused on the communications that are happening from the plans at this point in time to their patients making sure that doctors know about our vapa program and these wins that are going to be taking place to ultimately support the patient at the end of the year We have a very robust high-touch program that is taking place and activating as we speak now that will continue to wrap up the year to support these patients and really accelerate growth at the end of the year. we have a very robust high-touch program that is taking place and activating as we speak now that will continue to wrap up the year to support these patients and really accelerate growth at the end of the year I think, in addition, our program right now, our fill program in VAPA, is a very high-touch program. i think in addition our program right now our fill program in vapa is a very high-touch program We have a very, very clear view into who the patients are that are coming on our product and that are eligible for conversion to this commercial win. Super exciting time. To answer your question, we have a very clear plan to really drive conversion and help these patients. We have a very, very clear view into who the patients are that are coming on our product and that are eligible for conversion to this commercial win. we have a very very clear view into who the patients are that are coming on our product and that are eligible for conversion to this commercial win Super exciting time. super exciting time To answer your question, we have a very clear plan to really drive conversion and help these patients. to answer your question we have a very clear plan to really drive conversion and help these patients

Speaker 13: I'll just add that I was excited. As soon as we got the coverage win, we got that information, I'll tell you, and it gave me a lot of confidence in Pat and Maria and the team. I mean, I think they even had a name for the plan internally that they were going to begin to execute. It was just a text message. I'll just add that I was excited. i'll just add that i was excited As soon as we got the coverage win, we got that information, I'll tell you, and it gave me a lot of confidence in Pat and Maria and the team. as soon as we got the coverage win we got that information i'll tell you and it gave me a lot of confidence in pat and maria and the team I mean, I think they even had a name for the plan internally that they were going to begin to execute. i mean i think they even had a name for the plan internally that they were going to begin to execute It was just a text message. it was just a text message It was just like, "Okay, let's fire it up." It just gave me a lot of confidence that we have the right people, we have the right strategy to take advantage of this great opportunity and continue the growth in VEVYE. Kudos to the work that Pat and Maria are doing. It was just like, "Okay, let's fire it up." It just gave me a lot of confidence that we have the right people, we have the right strategy to take advantage of this great opportunity and continue the growth in VEVYE. it was just like "okay let's fire it up." it just gave me a lot of confidence that we have the right people we have the right strategy to take advantage of this great opportunity and continue the growth in vevye Kudos to the work that Pat and Maria are doing. kudos to the work that pat and maria are doing

Speaker 10: Thank you. Our next question comes from Mayank Mamtani with B. Riley Securities. Your line is open. Thank you. thank you Our next question comes from Mayank Mamtani with B. our next question comes from mayank mamtani with b Riley Securities. riley securities Your line is open. your line is open

Speaker 5: Yes, good morning, team. Thanks for taking our questions and appreciate the detail on business momentum. Maybe just a higher-level question on sort of these 3Q to 4Q dynamics. Some you observed last year versus others you're talking to are unique to you this year. I was just curious if you could comment a little bit on the notably high sort of $80 million revenue threshold in 4Q. Yes, good morning, team. yes good morning team Thanks for taking our questions and appreciate the detail on business momentum. thanks for taking our questions and appreciate the detail on business momentum Maybe just a higher-level question on sort of these 3Q to 4Q dynamics. maybe just a higher-level question on sort of these 3q to 4q dynamics Some you observed last year versus others you're talking to are unique to you this year. some you observed last year versus others you're talking to are unique to you this year I was just curious if you could comment a little bit on the notably high sort of $80 million revenue threshold in 4Q. i was just curious if you could comment a little bit on the notably high sort of $80 million revenue threshold in 4q It's sort of sequentially double versus what you had in 3Q. And it seems a lot to be still driven by VEVYE, I think 60% over. Sequentially. Any color, Mark, you can give on volume versus price kind of dynamic here that you're assuming across the different product lines. And then I have a follow-up. It's sort of sequentially double versus what you had in 3Q. it's sort of sequentially double versus what you had in 3q And it seems a lot to be still driven by VEVYE, I think 60% over. and it seems a lot to be still driven by vevye i think 60% over Sequentially. sequentially Any color, Mark, you can give on volume versus price kind of dynamic here that you're assuming across the different product lines. any color mark you can give on volume versus price kind of dynamic here that you're assuming across the different product lines And then I have a follow-up. and then i have a follow-up

Speaker 13: On Q4, what I would say is I think last year, Andrew, Q4 was probably upwards of a third, maybe a smidge higher than a third of our overall revenue for the annual period. I wouldn't expect that to change this year. I think that we can do around that range this year. I think the exciting thing about Q4 for what it's worth is the emergence of TRIESENCE finally. I think I was quite candid in the letter. We could have done a lot better. We should have done a lot better with TRIESENCE. On Q4, what I would say is I think last year, Andrew, Q4 was probably upwards of a third, maybe a smidge higher than a third of our overall revenue for the annual period. on q4 what i would say is i think last year andrew q4 was probably upwards of a third maybe a smidge higher than a third of our overall revenue for the annual period I wouldn't expect that to change this year. i wouldn't expect that to change this year I think that we can do around that range this year. i think that we can do around that range this year I think the exciting thing about Q4 for what it's worth is the emergence of TRIESENCE finally. i think the exciting thing about q4 for what it's worth is the emergence of triesence finally I think I was quite candid in the letter. i think i was quite candid in the letter We could have done a lot better. we could have done a lot better We should have done a lot better with TRIESENCE. we should have done a lot better with triesence In every period this year, the first three periods, the same is true with our rare and specialty portfolio. The key is that we've taken action. TRIESENCE, I think we're seeing really exciting things, not just in words, but in deeds. As I was telling the team, we're not at a point where Mark can get on a conference call and say, "Hey, I'm really excited about TRIESENCE. I think this is going to be fantastic." It is time for orders. It is time for revenue. It is time for reorders. It is time for new accounts starting and adopting. Because I'm seeing that, I'm actually—I have been involved in the sales process myself. I have been communicating with high-volume surgeons and talking to them about TRIESENCE specifically. I'm actually seeing surgeries start with it. That is exciting. I have been through that cycle. I have seen that cycle. In every period this year, the first three periods, the same is true with our rare and specialty portfolio. in every period this year the first three periods the same is true with our rare and specialty portfolio The key is that we've taken action. the key is that we've taken action TRIESENCE, I think we're seeing really exciting things, not just in words, but in deeds. triesence i think we're seeing really exciting things not just in words but in deeds As I was telling the team, we're not at a point where Mark can get on a conference call and say, "Hey, I'm really excited about TRIESENCE. as i was telling the team we're not at a point where mark can get on a conference call and say "hey i'm really excited about triesence I think this is going to be fantastic." It is time for orders. It is time for revenue. It is time for reorders. It is time for new accounts starting and adopting. i think this is going to be fantastic." it is time for orders. it is time for revenue. it is time for reorders. it is time for new accounts starting and adopting Because I'm seeing that, I'm actually—I have been involved in the sales process myself. I have been communicating with high-volume surgeons and talking to them about TRIESENCE specifically. because i'm seeing that i'm actually—i have been involved in the sales process myself. i have been communicating with high-volume surgeons and talking to them about triesence specifically I'm actually seeing surgeries start with it. i'm actually seeing surgeries start with it That is exciting. that is exciting I have been through that cycle. I have seen that cycle. i have been through that cycle. i have seen that cycle That gives me a lot of confidence in where we're going with that product, not only beginning to feather in in the fourth quarter, but really for next year. It's going to get to where we thought it would be. That's super important. In terms of other dynamics between Q3 and Q4, Andrew, do you want to comment on any of that? That gives me a lot of confidence in where we're going with that product, not only beginning to feather in in the fourth quarter, but really for next year. that gives me a lot of confidence in where we're going with that product not only beginning to feather in in the fourth quarter but really for next year It's going to get to where we thought it would be. it's going to get to where we thought it would be That's super important. that's super important In terms of other dynamics between Q3 and Q4, Andrew, do you want to comment on any of that? in terms of other dynamics between q3 and q4 andrew do you want to comment on any of that

Speaker 3: Yeah, Mike, I think we've kind of talked about VEVYE on the ASP side and expecting at least stabilization there. Typically, at the end of the year, your patients are out of that copay deductible and amounts like that. Our copay buy-downs are a little bit lower on a per-unit basis. Hopefully, that helps to see a little bit of price improvement. In general, the expectation is we're going to see volume improve across the portfolio. Yeah, Mike, I think we've kind of talked about VEVYE on the ASP side and expecting at least stabilization there. yeah mike i think we've kind of talked about vevye on the asp side and expecting at least stabilization there Typically, at the end of the year, your patients are out of that copay deductible and amounts like that. typically at the end of the year your patients are out of that copay deductible and amounts like that Our copay buy-downs are a little bit lower on a per-unit basis. our copay buy-downs are a little bit lower on a per-unit basis Hopefully, that helps to see a little bit of price improvement. hopefully that helps to see a little bit of price improvement In general, the expectation is we're going to see volume improve across the portfolio. in general the expectation is we're going to see volume improve across the portfolio That'll drive most of the revenue growth for the quarter. That'll drive most of the revenue growth for the quarter. that'll drive most of the revenue growth for the quarter

Speaker 5: Great. Actually, a couple of specific product-level questions. Project BYQLOVI enabled patients who crossed over to branded VEVYE. You may have some information there on the conversion rate from cash-pay maybe to commercial insurance coverage groups. I don't know if that was something you can share or has given you some learnings moving forward. On TRIESENCE, are you able to comment on what the new price point is? Looks like you're really focused on access to enable significant volume growth as you enter the ocular inflammation market. Obviously, very curious to hear your goal here, how close you are trying to get to when the product was not on the shortage list a few years ago. Thanks for taking our questions. Great. great Actually, a couple of specific product-level questions. actually a couple of specific product-level questions Project BYQLOVI enabled patients who crossed over to branded VEVYE. project byqlovi enabled patients who crossed over to branded vevye You may have some information there on the conversion rate from cash-pay maybe to commercial insurance coverage groups. you may have some information there on the conversion rate from cash-pay maybe to commercial insurance coverage groups I don't know if that was something you can share or has given you some learnings moving forward. i don't know if that was something you can share or has given you some learnings moving forward On TRIESENCE, are you able to comment on what the new price point is? on triesence are you able to comment on what the new price point is Looks like you're really focused on access to enable significant volume growth as you enter the ocular inflammation market. looks like you're really focused on access to enable significant volume growth as you enter the ocular inflammation market Obviously, very curious to hear your goal here, how close you are trying to get to when the product was not on the shortage list a few years ago. obviously very curious to hear your goal here how close you are trying to get to when the product was not on the shortage list a few years ago Thanks for taking our questions. thanks for taking our questions

Speaker 13: In terms of Project Beagle and specifically the transition from Clarity C to Vivi, we really do not have much more to add to that. I think we had more than 25,000 patients that were using cash-pay Clarity C. We stopped making Clarity C in the summertime. I think largely those conversions have taken place. There are probably some units out in the field in various offices around the country. I expect for that to be kind of mopped up by the end of the year for sure. Those patients who will have transitioned to Vivi will have made that transition. In terms of TRIESENCE pricing, the pricing was at $944. You are moving into the ocular inflammation market. The products in that category are probably 20%–25% lower in price. I believe, and I think our team believes, that price would have affected adoption. In terms of Project Beagle and specifically the transition from Clarity C to Vivi, we really do not have much more to add to that. in terms of project beagle and specifically the transition from clarity c to vivi we really do not have much more to add to that I think we had more than 25,000 patients that were using cash-pay Clarity C. i think we had more than 25,000 patients that were using cash-pay clarity c We stopped making Clarity C in the summertime. we stopped making clarity c in the summertime I think largely those conversions have taken place. There are probably some units out in the field in various offices around the country. i think largely those conversions have taken place. there are probably some units out in the field in various offices around the country I expect for that to be kind of mopped up by the end of the year for sure. i expect for that to be kind of mopped up by the end of the year for sure Those patients who will have transitioned to Vivi will have made that transition. those patients who will have transitioned to vivi will have made that transition In terms of TRIESENCE pricing, the pricing was at $944. in terms of triesence pricing the pricing was at $944 You are moving into the ocular inflammation market. you are moving into the ocular inflammation market The products in that category are probably 20%–25% lower in price. the products in that category are probably 20%–25% lower in price I believe, and I think our team believes, that price would have affected adoption. i believe and i think our team believes that price would have affected adoption In particular, as we focused on that ocular inflammation market, it was a good move, by the way. New orders are coming. As I said, it is not Mark talking about what might happen, what could happen. It is Mark talking about orders coming in, revenue, reorders. As I said in the stockholder letter, we have now confirmed reimbursement. You are talking about a product that has tremendous coverage, an extraordinarily low prior authorization rate, a multi-decade track record of performance. It is a product that is, I would say, beloved by ocular surgeons. There are a number of other reasons why, clinical reasons as well as economic reasons, why TRIESENCE is so exciting to these physicians that really did not know that this level of reimbursement was available for this product. We are seeing really positive things. I have been through this before. In particular, as we focused on that ocular inflammation market, it was a good move, by the way. in particular as we focused on that ocular inflammation market it was a good move by the way New orders are coming. new orders are coming As I said, it is not Mark talking about what might happen, what could happen. It is Mark talking about orders coming in, revenue, reorders. as i said, it is not mark talking about what might happen what could happen. it is mark talking about orders coming in revenue reorders As I said in the stockholder letter, we have now confirmed reimbursement. as i said in the stockholder letter we have now confirmed reimbursement You are talking about a product that has tremendous coverage, an extraordinarily low prior authorization rate, a multi-decade track record of performance. It is a product that is, I would say, beloved by ocular surgeons. you are talking about a product that has tremendous coverage an extraordinarily low prior authorization rate a multi-decade track record of performance. it is a product that is i would say beloved by ocular surgeons There are a number of other reasons why, clinical reasons as well as economic reasons, why TRIESENCE is so exciting to these physicians that really did not know that this level of reimbursement was available for this product. there are a number of other reasons why clinical reasons as well as economic reasons why triesence is so exciting to these physicians that really did not know that this level of reimbursement was available for this product We are seeing really positive things. we are seeing really positive things I have been through this before. i have been through this before Our first product was a product called Trimoxy. It was a compounded combination of triamcinolone acetonide and moxifloxacin hydrochloride. I remember the adoption cycle there. What happens in the surgical environment in particular is you get a few cases, I tried to describe it in the letter as stockholders, and then they see that it performs terrific clinically. Now we've gone through the reimbursement cycle. There's really no reason why these physicians can't use this pervasively throughout their practice. There is this cycle to adoption. We're going through those cycles right now. What's really neat is once those physicians adopt this and it starts working so well for their patients and they see their patients coming in with clean white eyes on their post-op day one, they don't want to change. Our first product was a product called Trimoxy. our first product was a product called trimoxy It was a compounded combination of triamcinolone acetonide and moxifloxacin hydrochloride. it was a compounded combination of triamcinolone acetonide and moxifloxacin hydrochloride I remember the adoption cycle there. i remember the adoption cycle there What happens in the surgical environment in particular is you get a few cases, I tried to describe it in the letter as stockholders, and then they see that it performs terrific clinically. what happens in the surgical environment in particular is you get a few cases i tried to describe it in the letter as stockholders and then they see that it performs terrific clinically Now we've gone through the reimbursement cycle. now we've gone through the reimbursement cycle There's really no reason why these physicians can't use this pervasively throughout their practice. there's really no reason why these physicians can't use this pervasively throughout their practice There is this cycle to adoption. there is this cycle to adoption We're going through those cycles right now. we're going through those cycles right now What's really neat is once those physicians adopt this and it starts working so well for their patients and they see their patients coming in with clean white eyes on their post-op day one, they don't want to change. what's really neat is once those physicians adopt this and it starts working so well for their patients and they see their patients coming in with clean white eyes on their post-op day one they don't want to change When they talk to their administrators at their surgery centers and they hear that they were reimbursed and they did not have to deal with prior authorization, they just do not want to change. It grows and grows and grows. At our peak with a non-FDA-approved compounded product, we were doing in excess of probably 300,000 units of Trimoxy and Trimoxy Venk years ago and some of these other sterile injectables. When I think about what TRIESENCE had done many years ago versus what we were doing with a non-FDA-approved product, which was significantly more than TRIESENCE in terms of annual unit volumes, I say that the units that we were doing with a non-FDA-approved product were minuscule relative to what the overall market opportunity is. I just wonder why any surgeon would not use TRIESENCE. When they talk to their administrators at their surgery centers and they hear that they were reimbursed and they did not have to deal with prior authorization, they just do not want to change. when they talk to their administrators at their surgery centers and they hear that they were reimbursed and they did not have to deal with prior authorization they just do not want to change It grows and grows and grows. it grows and grows and grows At our peak with a non-FDA-approved compounded product, we were doing in excess of probably 300,000 units of Trimoxy and Trimoxy Venk years ago and some of these other sterile injectables. at our peak with a non-fda-approved compounded product we were doing in excess of probably 300,000 units of trimoxy and trimoxy venk years ago and some of these other sterile injectables When I think about what TRIESENCE had done many years ago versus what we were doing with a non-FDA-approved product, which was significantly more than TRIESENCE in terms of annual unit volumes, I say that the units that we were doing with a non-FDA-approved product were minuscule relative to what the overall market opportunity is. when i think about what triesence had done many years ago versus what we were doing with a non-fda-approved product which was significantly more than triesence in terms of annual unit volumes i say that the units that we were doing with a non-fda-approved product were minuscule relative to what the overall market opportunity is I just wonder why any surgeon would not use TRIESENCE. i just wonder why any surgeon would not use triesence We think that this is going to become hopefully the new standard of care for these patients. If it was my mother, if it was someone that I loved that was having a procedure and they could have the physician inject the medication to ensure that they had the medication on board and that they would not have to, as a 75, 78, 80-year-old patient with comorbidities, have to administer eye drops post-surgery, I think I would want my mother's physician to choose TRIESENCE. We think more and more physicians will. It's an exciting time for that product. We're just scratching the surface. I don't even know that you could even call it a scratch at this point. We think that this is going to become hopefully the new standard of care for these patients. we think that this is going to become hopefully the new standard of care for these patients If it was my mother, if it was someone that I loved that was having a procedure and they could have the physician inject the medication to ensure that they had the medication on board and that they would not have to, as a 75, 78, 80-year-old patient with comorbidities, have to administer eye drops post-surgery, I think I would want my mother's physician to choose TRIESENCE. if it was my mother if it was someone that i loved that was having a procedure and they could have the physician inject the medication to ensure that they had the medication on board and that they would not have to as a 75 78 80-year-old patient with comorbidities have to administer eye drops post-surgery i think i would want my mother's physician to choose triesence We think more and more physicians will. we think more and more physicians will It's an exciting time for that product. it's an exciting time for that product We're just scratching the surface. we're just scratching the surface I don't even know that you could even call it a scratch at this point. i don't even know that you could even call it a scratch at this point

Speaker 5: Absolute color, Mark. Thank you. Absolute color, Mark. absolute color mark Thank you. thank you

Speaker 10: Thank you. Our next question comes from Tom Shrader with BTIG. Your line is open. Thank you. thank you Our next question comes from Tom Shrader with BTIG. our next question comes from tom shrader with btig Your line is open. your line is open

Speaker 8: Good morning. Congratulations on the quarter. Good morning. good morning Congratulations on the quarter. congratulations on the quarter The TRIESENCE, that had a pretty good user base before, and we agree people loved the drug. Is it easy to move back into those people, or have they moved on? Could you just give us a sense of is that low-hanging fruit? Are those people waiting for the drug? You commented on fueling commercial operations for VEVYE. Does that mean adding conventional salespeople? If so, what other products do you think they could most easily help? Is TRIESENCE too far away for someone to market both VEVYE and TRIESENCE? Thanks. The TRIESENCE, that had a pretty good user base before, and we agree people loved the drug. the triesence that had a pretty good user base before and we agree people loved the drug Is it easy to move back into those people, or have they moved on? is it easy to move back into those people or have they moved on Could you just give us a sense of is that low-hanging fruit? could you just give us a sense of is that low-hanging fruit are Are those people waiting for the drug? are those people waiting for the drug You commented on fueling commercial operations for VEVYE. you commented on fueling commercial operations for vevye Does that mean adding conventional salespeople? does that mean adding conventional salespeople If so, what other products do you think they could most easily help? if so what other products do you think they could most easily help Is TRIESENCE too far away for someone to market both VEVYE and TRIESENCE? is triesence too far away for someone to market both vevye and triesence Thanks. thanks

Speaker 13: I do not want to keep talking, but if you do not mind, I am going to take both if that is all right. In terms of how easy it is to reengage and whether these physicians have moved on, when TRIESENCE was not available, without question, they moved on. They started using Kenalog, which has preservatives. I do not want to keep talking, but if you do not mind, I am going to take both if that is all right. i do not want to keep talking but if you do not mind, i am going to take both if that is all right In terms of how easy it is to reengage and whether these physicians have moved on, when TRIESENCE was not available, without question, they moved on. in terms of how easy it is to reengage and whether these physicians have moved on when triesence was not available without question they moved on They started using Kenalog, which has preservatives. they started using kenalog which has preservatives It's got benzyl alcohol in it. If you're the patient, if the patient is someone you love, you don't want the doctor putting a chemical in their eye that could potentially blind them. That is why Alcon many years ago sought FDA approval for TRIESENCE because there was a clear unmet need in the marketplace for a preservative-free triamcinolone acetonide. That is TRIESENCE. That's what makes the product very special. If you knew that an iPhone 17 was not available, maybe you'd go back to the BlackBerry. Boy, as soon as you found out that the iPhone 17 was available, you're going to switch back. It does take time to reengage with these physicians. Many of them, even to this day, don't know that TRIESENCE is available, that it's in stock. They don't know about the low prior authorization rate, the reimbursement and coverage. It's got benzyl alcohol in it. it's got benzyl alcohol in it If you're the patient, if the patient is someone you love, you don't want the doctor putting a chemical in their eye that could potentially blind them. if you're the patient if the patient is someone you love you don't want the doctor putting a chemical in their eye that could potentially blind them That is why Alcon many years ago sought FDA approval for TRIESENCE because there was a clear unmet need in the marketplace for a preservative-free triamcinolone acetonide. that is why alcon many years ago sought fda approval for triesence because there was a clear unmet need in the marketplace for a preservative-free triamcinolone acetonide That is TRIESENCE. that is triesence That's what makes the product very special. that's what makes the product very special If you knew that an iPhone 17 was not available, maybe you'd go back to the BlackBerry. if you knew that an iphone 17 was not available maybe you'd go back to the blackberry Boy, as soon as you found out that the iPhone 17 was available, you're going to switch back. boy as soon as you found out that the iphone 17 was available you're going to switch back It does take time to reengage with these physicians. it does take time to reengage with these physicians Many of them, even to this day, don't know that TRIESENCE is available, that it's in stock. many of them even to this day don't know that triesence is available that it's in stock They don't know about the low prior authorization rate, the reimbursement and coverage. they don't know about the low prior authorization rate the reimbursement and coverage That is our job. That is Chad's job. That is the job of this team that is going out, Aly and her folks and Adam, and really making it happen for this product. It takes time. I mean, you are talking about thousands and thousands of call points, but they are doing a great job. They are making progress. I think Pat talked about that. For Harrow and our stockholders, the juice will be worth a squeeze. I mean, this is a tremendous product. I have always said that I saw TRIESENCE as a nine-figure revenue product. I think we are going to get there in due course. You would not think that from the first quarter, the second quarter, and the third quarter. I think if we speak this time next year, you will see that I was not delusional. That is our job. That is Chad's job. That is the job of this team that is going out, Aly and her folks and Adam, and really making it happen for this product. that is our job. that is chad's job. that is the job of this team that is going out aly and her folks and adam and really making it happen for this product It takes time. it takes time I mean, you are talking about thousands and thousands of call points, but they are doing a great job. They are making progress. i mean, you are talking about thousands and thousands of call points but they are doing a great job. they are making progress I think Pat talked about that. i think pat talked about that For Harrow and our stockholders, the juice will be worth a squeeze. for harrow and our stockholders the juice will be worth a squeeze I mean, this is a tremendous product. I have always said that I saw TRIESENCE as a nine-figure revenue product. i mean this is a tremendous product. i have always said that i saw triesence as a nine-figure revenue product I think we are going to get there in due course. i think we are going to get there in due course You would not think that from the first quarter, the second quarter, and the third quarter. you would not think that from the first quarter the second quarter and the third quarter I think if we speak this time next year, you will see that I was not delusional. i think if we speak this time next year you will see that i was not delusional Finally, in terms of commercial ops for VEVYE, we're making those investments because we have coverage. When you have coverage, when you have the ability to have a prescription written and to get it filled in sort of a friction-free way. What we do know, by the way, and we've talked about this in prior stockholder letters, is that when we get a commercially covered VEVYE patient through our process, we retain them. Our refill rate is amazing for a commercially covered patient. Once we get that patient, now that we can get them covered, we can retain them because the product is so spectacular. It provides us with a sort of a compounding effect as we would get more new patients and retain them. You'll see that continued growth. Finally, in terms of commercial ops for VEVYE, we're making those investments because we have coverage. finally in terms of commercial ops for vevye we're making those investments because we have coverage When you have coverage, when you have the ability to have a prescription written and to get it filled in sort of a friction-free way. when you have coverage when you have the ability to have a prescription written and to get it filled in sort of a friction-free way What we do know, by the way, and we've talked about this in prior stockholder letters, is that when we get a commercially covered VEVYE patient through our process, we retain them. what we do know by the way and we've talked about this in prior stockholder letters is that when we get a commercially covered vevye patient through our process we retain them Our refill rate is amazing for a commercially covered patient. our refill rate is amazing for a commercially covered patient Once we get that patient, now that we can get them covered, we can retain them because the product is so spectacular. once we get that patient now that we can get them covered we can retain them because the product is so spectacular It provides us with a sort of a compounding effect as we would get more new patients and retain them. it provides us with a sort of a compounding effect as we would get more new patients and retain them You'll see that continued growth. you'll see that continued growth In terms of other products that we're going to put in their bag, if you go through the corporate deck, one of the things I'm really excited about is we actually did add two products to the bag of our dry eye team. We have an amazing dry eye team. It will be growing. As I said, by the middle of next year, we'll have 100 territories. Maria's going to have a much larger group of folks to manage. They will also be helping patients and giving them access to Flarex. They'll have Freshco in their bag as well. In terms of other products that we're going to put in their bag, if you go through the corporate deck, one of the things I'm really excited about is we actually did add two products to the bag of our dry eye team. in terms of other products that we're going to put in their bag if you go through the corporate deck one of the things i'm really excited about is we actually did add two products to the bag of our dry eye team We have an amazing dry eye team. we have an amazing dry eye team It will be growing. it will be growing As I said, by the middle of next year, we'll have 100 territories. as i said by the middle of next year we'll have 100 territories Maria's going to have a much larger group of folks to manage. maria's going to have a much larger group of folks to manage They will also be helping patients and giving them access to Flarex. they will also be helping patients and giving them access to flarex They'll have Freshco in their bag as well. they'll have freshco in their bag as well The combination of a chronic care dry eye medication with other related products that cover ocular inflammation and Freshco in particular, which I think if you Google Freshco, you start looking at some of the marketing materials and its ability through polyvinyl alcohol base to actually help patients retain their tears and prevent evaporation. I think that's a really terrific product that the team is excited about. By the way, it's over the counter. I think you can get it for under $30 a unit. It's over the counter, so you don't need a prescription for it. We're going to do some exciting things with Freshco. Maria's got Flarex now. Of course, the cornerstone product in her portfolio is VEVYE The combination of a chronic care dry eye medication with other related products that cover ocular inflammation and Freshco in particular, which I think if you Google Freshco, you start looking at some of the marketing materials and its ability through polyvinyl alcohol base to actually help patients retain their tears and prevent evaporation. the combination of a chronic care dry eye medication with other related products that cover ocular inflammation and freshco in particular which i think if you google freshco you start looking at some of the marketing materials and its ability through polyvinyl alcohol base to actually help patients retain their tears and prevent evaporation I think that's a really terrific product that the team is excited about. i think that's a really terrific product that the team is excited about By the way, it's over the counter. by the way it's over the counter I think you can get it for under $30 a unit. i think you can get it for under $30 a unit It's over the counter, so you don't need a prescription for it. it's over the counter so you don't need a prescription for it We're going to do some exciting things with Freshco. we're going to do some exciting things with freshco Maria's got Flarex now. maria's got flarex now Of course, the cornerstone product in her portfolio is VEVYE of course the cornerstone product in her portfolio is vevye

Speaker 8: Got it. Right. Thanks for the detail. Got it. got it Right. right Thanks for the detail. thanks for the detail

Speaker 13: Thank you, Tom. Thank you, Tom. thank you tom

Speaker 10: Thank you. Our next question comes from Lachlan Hanbury–Brown with William Blair. Thank you. thank you Our next question comes from Lachlan Hanbury– Brown with William Blair. our next question comes from lachlan hanbury– brown with william blair Your line is open. Your line is open. your line is open

Speaker 11: Hey, guys. Thanks for the questions. I guess I'd be curious on the new coverage for VEVYE. Can you just talk about how the economics there shake up or stack up compared to the current net pricing you're seeing? Because I know you've been sort of vocal, Mark, in the past about the economics that PBMs try to extract. It would be interesting to know just sort of where that shakes out. Also, once those new plans come online in 2026, what kind of coverage level are you looking at? What proportion of commercial lives nationally are covered for VEVYE? Hey, guys. hey guys Thanks for the questions. thanks for the questions I guess I'd be curious on the new coverage for VEVYE. i guess i'd be curious on the new coverage for vevye Can you just talk about how the economics there shake up or stack up compared to the current net pricing you're seeing? can you just talk about how the economics there shake up or stack up compared to the current net pricing you're seeing Because I know you've been sort of vocal, Mark, in the past about the economics that PBMs try to extract. because i know you've been sort of vocal mark in the past about the economics that pbms try to extract It would be interesting to know just sort of where that shakes out. it would be interesting to know just sort of where that shakes out Also, once those new plans come online in 2026, what kind of coverage level are you looking at? also once those new plans come online in 2026 what kind of coverage level are you looking at What proportion of commercial lives nationally are covered for VEVYE? what proportion of commercial lives nationally are covered for vevye

Speaker 13: What I can tell you, and Andrew mentioned this, is that when you have a VAFA program and you establish a base, it takes you out of what we would call desperation mode to do bad deals with PBMs. What I can tell you, and Andrew mentioned this, is that when you have a VAFA program and you establish a base, it takes you out of what we would call desperation mode to do bad deals with PBMs. what i can tell you and andrew mentioned this is that when you have a vafa program and you establish a base it takes you out of what we would call desperation mode to do bad deals with pbms Andrew, do you want to kind of add to that? You talked about it a little while earlier. Andrew, do you want to kind of add to that? andrew do you want to kind of add to that You talked about it a little while earlier. you talked about it a little while earlier

Speaker 3: Yeah. Without giving away the kind of bid, like Mark was saying, like I was saying, we kind of start with a base and we say, "Okay, if we're going to get a coverage win, what do we want? What does the economics need to be?" It obviously has to be an improvement on the cash number that we have. What that means and what I think, and without being specific about what that impact is going to be, the expectation is it's going to be an improvement for those patients over the cash price that we would net on a per-unit basis. We've talked a lot about just the ASP impact of the coverage win and that it'll help stabilize and certainly increase that number in 2026. Yeah. yeah Without giving away the kind of bid, like Mark was saying, like I was saying, we kind of start with a base and we say, "Okay, if we're going to get a coverage win, what do we want? without giving away the kind of bid like mark was saying like i was saying we kind of start with a base and we say "okay if we're going to get a coverage win what do we want what does What does the economics need to be?" It obviously has to be an improvement on the cash number that we have. want what does the economics need to be?" it obviously has to be an improvement on the cash number that we have What that means and what I think, and without being specific about what that impact is going to be, the expectation is it's going to be an improvement for those patients over the cash price that we would net on a per-unit basis. what that means and what i think and without being specific about what that impact is going to be the expectation is it's going to be an improvement for those patients over the cash price that we would net on a per-unit basis We've talked a lot about just the ASP impact of the coverage win and that it'll help stabilize and certainly increase that number in 2026. we've talked a lot about just the asp impact of the coverage win and that it'll help stabilize and certainly increase that number in 2026 There's another aspect to this, which is VEVYE was not preferred in this plan. Mark kind of talked about this. The fact that now it is preferred and another product got pulled out of that preferred status, the payer is letting the physicians know, "Hey, your patient was on this product and it's not going to be preferred next year, but VEVYE is." Not only are we going to get the increase in ASP, but just getting that preferred status, the PBM is helping us drive volume. You're going to kind of one begets the other, but it's going to be an increase in ASP. It should also be an increase in volume as well for the product. There's another aspect to this, which is VEVYE was not preferred in this plan. there's another aspect to this which is vevye was not preferred in this plan Mark kind of talked about this. mark kind of talked about this The fact that now it is preferred and another product got pulled out of that preferred status, the payer is letting the physicians know, "Hey, your patient was on this product and it's not going to be preferred next year, but VEVYE is." Not only are we going to get the increase in ASP, but just getting that preferred status, the PBM is helping us drive volume. the fact that now it is preferred and another product got pulled out of that preferred status the payer is letting the physicians know "hey your patient was on this product and it's not going to be preferred next year but vevye is." not only are we going to get the increase in asp but just getting that preferred status the pbm is helping us drive volume You're going to kind of one begets the other, but it's going to be an increase in ASP. you're going to kind of one begets the other but it's going to be an increase in asp It should also be an increase in volume as well for the product. it should also be an increase in volume as well for the product

Speaker 11: All right. Great. Thanks. Maybe a quick one on the VEVYE expansion, the new territory. All right. all right Great. great Thanks. thanks Maybe a quick one on the VEVYE expansion, the new territory. maybe a quick one on the vevye expansion the new territory Just to make sure I heard correctly, is that you're adding 10 new reps this quarter, and then we'll keep adding more until you get to about 100 next year, which, if I have my numbers right, is sort of roughly double where you're at now? Just to make sure I heard correctly, is that you're adding 10 new reps this quarter, and then we'll keep adding more until you get to about 100 next year, which, if I have my numbers right, is sort of roughly double where you're at now? just to make sure i heard correctly is that you're adding 10 new reps this quarter and then we'll keep adding more until you get to about 100 next year which if i have my numbers right is sort of roughly double where you're at now

Speaker 13: Yeah. We're going to increase by 10. We'll get to a little bit more than 60 here in the very near term. By the second quarter, we'll hopefully have—we'll reach the century mark. We'll have about 100 territories. Yeah. yeah We're going to increase by 10. we're going to increase by 10 We'll get to a little bit more than 60 here in the very near term. we'll get to a little bit more than 60 here in the very near term By the second quarter, we'll hopefully have—we'll reach the century mark. by the second quarter we'll hopefully have—we'll reach the century mark We'll have about 100 territories. we'll have about 100 territories

Speaker 11: Awesome. Thanks. Awesome. awesome Thanks. thanks

Speaker 13: Thank you, Lachlan. Thank you, Lachlan. thank you lachlan

Speaker 10: Thank you. Our next question comes from Thomas Flaten with Lake Street Capital Markets. Your line is open. Thank you. thank you Our next question comes from Thomas Flaten with Lake Street Capital Markets. our next question comes from thomas flaten with lake street capital markets Your line is open. your line is open

Speaker 2: Hey, good morning. I appreciate you taking the questions. Hey, Mark, just to follow up, you mentioned the refill rates are great. Hey, good morning. hey good morning I appreciate you taking the questions. i appreciate you taking the questions Hey, Mark, just to follow up, you mentioned the refill rates are great. hey mark just to follow up you mentioned the refill rates are great Could you give us a sense of duration of therapy that some of these long-duration patients are on products for? Could you give us a sense of duration of therapy that some of these long-duration patients are on products for? could you give us a sense of duration of therapy that some of these long-duration patients are on products for

Speaker 13: I think last time that we looked at the data for a commercially covered patient, if you look at their initial prescription plus the refills and you add, you just think about the number of drops per bottle and the number of dosages per day. I mean, I think we were almost, we were right at these commercially covered patients getting therapy for the entirety of the year. I mean, I think it was only a few weeks away from, on average, refilling for the entirety of the year. I mean, we would have never, ever thought that we would get that sort of affinity of refill rate for that patient. I mean, that was not anywhere, even in the highest, the bullest of bull cases in our models. I think last time that we looked at the data for a commercially covered patient, if you look at their initial prescription plus the refills and you add, you just think about the number of drops per bottle and the number of dosages per day. i think last time that we looked at the data for a commercially covered patient if you look at their initial prescription plus the refills and you add you just think about the number of drops per bottle and the number of dosages per day I mean, I think we were almost, we were right at these commercially covered patients getting therapy for the entirety of the year. i mean i think we were almost we were right at these commercially covered patients getting therapy for the entirety of the year I mean, I think it was only a few weeks away from, on average, refilling for the entirety of the year. i mean i think it was only a few weeks away from on average refilling for the entirety of the year I mean, we would have never, ever thought that we would get that sort of affinity of refill rate for that patient. i mean we would have never ever thought that we would get that sort of affinity of refill rate for that patient I mean, that was not anywhere, even in the highest, the bullest of bull cases in our models. i mean that was not anywhere even in the highest the bullest of bull cases in our models That's what we've seen. Andrew, you want to add to that at all? That's what we've seen. that's what we've seen Andrew, you want to add to that at all? andrew you want to add to that at all

Speaker 3: No, nothing else. No, nothing else. no nothing else

Speaker 2: Maybe if I could, bigger picture, you guys have been pretty busy on the BD front and have kind of created a really impressive to-do list for yourselves over the next couple of years. What should we anticipate in 2026, 2027? Is this more of an absorb, digest, and act, or is it more deals, more deals? Where do you land on that? Maybe if I could, bigger picture, you guys have been pretty busy on the BD front and have kind of created a really impressive to-do list for yourselves over the next couple of years. maybe if i could bigger picture you guys have been pretty busy on the bd front and have kind of created a really impressive to-do list for yourselves over the next couple of years What should we anticipate in 2026, 2027? what should we anticipate in 2026 2027 Is this more of an absorb, digest, and act, or is it more deals, more deals? is this more of an absorb digest and act or is it more deals more deals Where do you land on that? where do you land on that

Speaker 13: I think at our office today and over the next week or so, we are over the moon excited about Melt. I don't think we've talked about Melt really at all, but we're hoping to get this closed here in the very near term. I don't think people really understand the value of Melt and what the potential is there. I think at our office today and over the next week or so, we are over the moon excited about Melt. i think at our office today and over the next week or so we are over the moon excited about melt I don't think we've talked about Melt really at all, but we're hoping to get this closed here in the very near term. i don't think we've talked about melt really at all but we're hoping to get this closed here in the very near term I don't think people really understand the value of Melt and what the potential is there. i don't think people really understand the value of melt and what the potential is there It's really transformative for us. Yeah, we look at deals constantly. We're always evaluating things. If you look at our portfolio and you think about some of the strategic goals that we've discussed and I've laid out even in the letter, in particular around cataract surgery, the vision for ophthalmic surgery that we have, which is to have opioid, IV, and drop-free cataract surgery, that's exciting for patients. That's transformative. The idea that you can probably go into an office, have office-based, maybe even bilateral same-day cataract surgery, and on the pharma side, have no IVs, no opioids, and not need eye drops post-surgery, that's extraordinary. That's what Melt and some of the other products that we have will enable. That's transformative for the nearly 5 million surgeries that occur annually in the US. We are looking at other deals. It's really transformative for us. it's really transformative for us Yeah, we look at deals constantly. yeah we look at deals constantly We're always evaluating things. we're always evaluating things If you look at our portfolio and you think about some of the strategic goals that we've discussed and I've laid out even in the letter, in particular around cataract surgery, the vision for ophthalmic surgery that we have, which is to have opioid, IV, and drop-free cataract surgery, that's exciting for patients. if you look at our portfolio and you think about some of the strategic goals that we've discussed and i've laid out even in the letter in particular around cataract surgery the vision for ophthalmic surgery that we have which is to have opioid iv and drop-free cataract surgery that's exciting for patients That's transformative. that's transformative The idea that you can probably go into an office, have office-based, maybe even bilateral same-day cataract surgery, and on the pharma side, have no IVs, no opioids, and not need eye drops post-surgery, that's extraordinary. the idea that you can probably go into an office have office-based maybe even bilateral same-day cataract surgery and on the pharma side have no ivs no opioids and not need eye drops post-surgery that's extraordinary That's what Melt and some of the other products that we have will enable. that's what melt and some of the other products that we have will enable That's transformative for the nearly 5 million surgeries that occur annually in the US. that's transformative for the nearly 5 million surgeries that occur annually in the us We are looking at other deals. we are looking at other deals We're very interested in other deals. Right now, we're super pumped about Melt. We want to get that closed. We want to get the balance of the data collected and put into a dossier so that we can submit an NDA and get that product approved and help realize this vision that we have to really transform ophthalmic surgery. Eventually, hopefully see the Melt 300 drug candidate used outside of ophthalmology, which is really a much bigger market opportunity in dental and GI and claustrophobia for MRIs and the tens of millions of annual uses in the US where we think the Melt 300 will be impactful. Of course, what's also interesting is this will be the first global play that we have. Historically, we've been a US-focused business. We're very interested in other deals. we're very interested in other deals Right now, we're super pumped about Melt. right now we're super pumped about melt We want to get that closed. we want to get that closed We want to get the balance of the data collected and put into a dossier so that we can submit an NDA and get that product approved and help realize this vision that we have to really transform ophthalmic surgery. we want to get the balance of the data collected and put into a dossier so that we can submit an nda and get that product approved and help realize this vision that we have to really transform ophthalmic surgery Eventually, hopefully see the Melt 300 drug candidate used outside of ophthalmology, which is really a much bigger market opportunity in dental and GI and claustrophobia for MRIs and the tens of millions of annual uses in the US where we think the Melt 300 will be impactful. eventually hopefully see the melt 300 drug candidate used outside of ophthalmology which is really a much bigger market opportunity in dental and gi and claustrophobia for mris and the tens of millions of annual uses in the us where we think the melt 300 will be impactful Of course, what's also interesting is this will be the first global play that we have. of course what's also interesting is this will be the first global play that we have Historically, we've been a US-focused business. historically we've been a us-focused business As you, I think, know, Melt 300 is not only patented, multiple patents issued domestically, but in many of the major markets around the world. It is a global opportunity as well that we hope to discuss with partners and other markets around the world. Lots to look at, but I'll tell you, when we look at what we have with Melt and the products that we've acquired over the years recently, we have just something very, very special that we need to execute on. I'm really pleased to have Pat as my partner, our partner to help us do that. As you, I think, know, Melt 300 is not only patented, multiple patents issued domestically, but in many of the major markets around the world. as you i think know melt 300 is not only patented multiple patents issued domestically but in many of the major markets around the world It is a global opportunity as well that we hope to discuss with partners and other markets around the world. it is a global opportunity as well that we hope to discuss with partners and other markets around the world Lots to look at, but I'll tell you, when we look at what we have with Melt and the products that we've acquired over the years recently, we have just something very, very special that we need to execute on. lots to look at but i'll tell you when we look at what we have with melt and the products that we've acquired over the years recently we have just something very very special that we need to execute on I'm really pleased to have Pat as my partner, our partner to help us do that. i'm really pleased to have pat as my partner our partner to help us do that

Speaker 2: I appreciate that. Thanks, Mark. I appreciate that. i appreciate that Thanks, Mark. thanks mark

Speaker 13: Thank you, Thomas. Thank you, Thomas. thank you thomas

Speaker 10: Thank you. Our next question comes from Yi Chen with HC Wainwright. Your line is open. Thank you. thank you Our next question comes from Yi Chen with HC Wainwright. our next question comes from yi chen with hc wainwright Your line is open. your line is open

Speaker 9: Good morning. Thank you for taking my question. Good morning. good morning Thank you for taking my question. thank you for taking my question Mark, you mentioned that with the coverage wing, some prescriptions fled to VEVYE. Could you give some additional color on market dynamics, whether those prescriptions fled to VEVYE? They originally came from prescriptions for other cyclosporine formulations, or they could come from non-cyclosporine prescriptions as well. Mark, you mentioned that with the coverage wing, some prescriptions fled to VEVYE. mark you mentioned that with the coverage wing some prescriptions fled to vevye Could you give some additional color on market dynamics, whether those prescriptions fled to VEVYE? could you give some additional color on market dynamics whether those prescriptions fled to vevye They originally came from prescriptions for other cyclosporine formulations, or they could come from non-cyclosporine prescriptions as well. they originally came from prescriptions for other cyclosporine formulations or they could come from non-cyclosporine prescriptions as well

Speaker 13: Thank you. Yeah. In terms of which product incurred the loss to our potential win, it was really, and I do not want to go into the specific products, but they were not cyclosporine-based products, but they were anti-inflammatories. You might be able to figure out which ones they were. In any case, for us, we are really focused on being the number one cyclosporine in the market. I think this really adds to that momentum. I think to be the number one cyclosporine in the market, you are talking about, I think with generics, probably 20-23% market share. Thank you. thank you Yeah. yeah In terms of which product incurred the loss to our potential win, it was really, and I do not want to go into the specific products, but they were not cyclosporine-based products, but they were anti-inflammatories. in terms of which product incurred the loss to our potential win it was really and i do not want to go into the specific products but they were not cyclosporine-based products but they were anti-inflammatories You might be able to figure out which ones they were. you might be able to figure out which ones they were In any case, for us, we are really focused on being the number one cyclosporine in the market. in any case for us we are really focused on being the number one cyclosporine in the market I think this really adds to that momentum. i think this really adds to that momentum I think to be the number one cyclosporine in the market, you are talking about, I think with generics, probably 20-23% market share. i think to be the number one cyclosporine in the market, you are talking about i think with generics probably 20-23% market share We're at a little over 10. We do expect to see NPP improvement as we get more and more coverage and that ratio flips. This is going to really help us, I think, drive not only new prescriptions from patients naturally, but I think from these flips. As I said, I've seen the letters that have gone out to the eye care professionals. It lists the product that is no longer covered, and it lists the patients. I know from the few physicians that I've spoken to that their intention is to move them to VEVYE. However, I have to say, if you go around the country, there are many physicians in many markets all over the country that have no idea what VEVYE is. We're at a little over 10. we're at a little over 10 We do expect to see NPP improvement as we get more and more coverage and that ratio flips. we do expect to see npp improvement as we get more and more coverage and that ratio flips This is going to really help us, I think, drive not only new prescriptions from patients naturally, but I think from these flips. this is going to really help us i think drive not only new prescriptions from patients naturally but i think from these flips As I said, I've seen the letters that have gone out to the eye care professionals. as i said i've seen the letters that have gone out to the eye care professionals It lists the product that is no longer covered, and it lists the patients. it lists the product that is no longer covered and it lists the patients I know from the few physicians that I've spoken to that their intention is to move them to VEVYE. i know from the few physicians that i've spoken to that their intention is to move them to vevye However, I have to say, if you go around the country, there are many physicians in many markets all over the country that have no idea what VEVYE is. however i have to say if you go around the country there are many physicians in many markets all over the country that have no idea what vevye is It is our job to make sure that they not only know about the clinical value that VEVYE brings, but also now the new coverage, which will, I think, create a more friction-free process for prescribing. It is our job to make sure that they not only know about the clinical value that VEVYE brings, but also now the new coverage, which will, I think, create a more friction-free process for prescribing. it is our job to make sure that they not only know about the clinical value that vevye brings but also now the new coverage which will i think create a more friction-free process for prescribing

Speaker 9: Thank you. Thank you. thank you

Speaker 3: Thank you, Yi. Thank you, Yi. thank you yi

Speaker 10: Thank you. I'm sure no further questions. I'd like to turn the call back over to Mark L. Baum, CEO, for closing remarks. Thank you. thank you I'm sure no further questions. i'm sure no further questions I'd like to turn the call back over to Mark L. i'd like to turn the call back over to mark l Baum, CEO, for closing remarks. baum ceo for closing remarks

Speaker 13: Thank you, operator. Thanks, everyone, for their questions. We really appreciate you joining us today. As we look into the future, I remain confident in where we're heading. We've built a solid foundation. We've brought together an outstanding leadership team and defined a clear strategy that touches every part of our business. We have a portfolio of best-in-class products and expanding access for patients and physicians and driving a culture that thrives on focus and execution. Thank you, operator. thank you operator Thanks, everyone, for their questions. thanks everyone for their questions We really appreciate you joining us today. we really appreciate you joining us today As we look into the future, I remain confident in where we're heading. as we look into the future i remain confident in where we're heading We've built a solid foundation. we've built a solid foundation We've brought together an outstanding leadership team and defined a clear strategy that touches every part of our business. we've brought together an outstanding leadership team and defined a clear strategy that touches every part of our business We have a portfolio of best-in-class products and expanding access for patients and physicians and driving a culture that thrives on focus and execution. we have a portfolio of best-in-class products and expanding access for patients and physicians and driving a culture that thrives on focus and execution It positions Harrow for sustained growth and long-term value creation. The opportunities that we have ahead of us with TRIESENCE and VEVYE and IHEEZO are tremendous, and we are ready to capture them. If you have any further questions or you need additional information, please do not hesitate to reach out to Mike Biega. His email address is M as in Mary, B as in Bravo, I-E-G-A at harrowinc.com. This will conclude our call. It positions Harrow for sustained growth and long-term value creation. it positions harrow for sustained growth and long-term value creation The opportunities that we have ahead of us with TRIESENCE and VEVYE and IHEEZO are tremendous, and we are ready to capture them. the opportunities that we have ahead of us with triesence and vevye and iheezo are tremendous and we are ready to capture them If you have any further questions or you need additional information, please do not hesitate to reach out to Mike Biega. if you have any further questions or you need additional information please do not hesitate to reach out to mike biega His email address is M as in Mary, B as in Bravo, I-E-G-A at harrowinc.com. his email address is m as in mary b as in bravo i-e-g-a at harrowinc.com This will conclude our call. this will conclude our call Thank you for your participation. You may now disconnect. Good day. Thank you for your participation. thank you for your participation You may now disconnect. you may now disconnect Good day. good day